Traceable Trust for action-ready artificial intelligence in bioscience

📅 2026-08-18
📈 Citations: 0
Influential: 0
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🤖 AI Summary
本文提出Traceable Trust框架,以评估和设计AI输出到生物科学研究行动的转化过程,确保其可信度。
📝 Abstract
Artificial intelligence (AI) is becoming part of the working infrastructure of the biosciences. AI models can predict biomolecular structures, design proteins, rank variants, annotate images, recommend strains and optimise experimental conditions. We argue that the decision to use an AI output to guide laboratory action is a key juncture for trustworthy research and should follow a defined, reviewable process. We propose Traceable Trust as a proportionate assessment-and-design framework for this output-to-action boundary. It asks what evidence supports the output, what capability is being claimed, what agency has been delegated, what threshold authorises action, who can override it and how outcomes inform later decisions. We illustrate the framework through three case studies spanning ecosystem resources, project design and laboratory action. Together, the cases show how trust can be documented where AI outputs begin to shape scientific work.
Problem

Research questions and friction points this paper is trying to address.

Artificial Intelligence
Trustworthy Research
Biosciences
Laboratory Action
Traceable Trust
Innovation

Methods, ideas, or system contributions that make the work stand out.

Traceable Trust
output-to-action boundary
trustworthy research
AI in bioscience
reviewable process
H
Huayu Xin
Science, Technology and Innovation Studies, School of Social and Political Science, University of Edinburgh, Edinburgh, UK.
Yizhi Cai
Yizhi Cai
Manchester Institute of Biotechnology, University of Manchester, Manchester, UK.
M
Mukilan Deivarajan Suresh
School of Natural and Environmental Sciences, Newcastle University, Newcastle upon Tyne, UK.; School of Computing, Newcastle University, Newcastle upon Tyne, UK.; Protecting Crops and Environment, Rothamsted Research, Harpenden, UK.
G
Gavin Michael Farrell
Department of Biomedical Sciences, University of Padova, Padova, Italy.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK.
I
Iwona Gajda
Bristol Robotics Laboratory, University of the West of England, Bristol, UK.
Charlie Harrison
Charlie Harrison
Google
Privacy
C
Conor Houghton
School of Engineering Mathematics and Technology, University of Bristol, Bristol, UK.
Mato Lagator
Mato Lagator
Division of Evolution, Infection and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Y
Yang Lu
Department of Computer Science, School of Science, Loughborough University, Loughborough, UK.
V
Virginia Portillo
School of Computer Science, University of Nottingham, Nottingham, UK.
Reyer Zwiggelaar
Reyer Zwiggelaar
Department of Computer Science, Aberystwyth University
S
Sebastian Lobentanzer
Helmholtz AI, Artificial Intelligence Cooperation Unit of the Helmholtz Association, Germany.; Institute of Computational Biology, Computational Health Center, Helmholtz Center, Munich, Germany.; School of Computation, Information and Technology, Technical University of Munich, Germany.; German Center for Diabetes Research, Munich, Germany.