Towards Patient-Specific Deformable Registration in Laparoscopic Surgery

πŸ“… 2026-04-14
πŸ“ˆ Citations: 0
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πŸ€– AI Summary
This study addresses the challenge of accurately registering preoperative 3D organ models to intraoperative scenes in laparoscopic surgery, where tissue deformation and noise hinder precise alignment, thereby limiting visualization-guided navigation and surgical safety. To overcome this, the work proposes the first patient-specific non-rigid point cloud registration method, integrating a Transformer encoder-decoder architecture with an overlap estimation module and a dedicated matching component to predict dense correspondences. A physics-driven deformation algorithm is further introduced to achieve high-fidelity personalized registration. Leveraging a novel patient-tailored data generation strategy, the method significantly outperforms existing general-purpose approaches, attaining a 45% matching score on synthetic data and a 92% inlier ratio on real clinical data, thereby substantially enhancing surgical navigation accuracy.

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πŸ“ Abstract
Unsafe surgical care is a critical health concern, often linked to limitations in surgeon experience, skills, and situational awareness. Integrating patient-specific 3D models into the surgical field can enhance visualization, provide real-time anatomical guidance, and reduce intraoperative complications. However, reliably registering these models in general surgery remains challenging due to mismatches between preoperative and intraoperative organ surfaces, such as deformations and noise. To overcome these challenges, we introduce the first patient-specific non-rigid point cloud registration method, which leverages a novel data generation strategy to optimize outcomes for individual patients. Our approach combines a Transformer encoder-decoder architecture with overlap estimation and a dedicated matching module to predict dense correspondences, followed by a physics-based algorithm for registration. Experimental results on both synthetic and real data demonstrate that our patient-specific method significantly outperforms traditional agnostic approaches, achieving 45% Matching Score with 92% Inlier Ratio on synthetic data, highlighting its potential to improve surgical care.
Problem

Research questions and friction points this paper is trying to address.

deformable registration
laparoscopic surgery
patient-specific
point cloud registration
organ deformation
Innovation

Methods, ideas, or system contributions that make the work stand out.

patient-specific
non-rigid registration
point cloud
Transformer architecture
physics-based registration
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A
Alberto Neri
Biomedical Robotics Lab, Istituto Italiano di Tecnologia, Genoa, Italy; Department of Computer Science, Bioengineering, Robotics and Systems Engineering (DIBRIS), University of Genoa, Italy; Harvard Medical School, Brigham and Women’s Hospital, Boston, USA
Veronica Penza
Veronica Penza
Researcher at Biomedical Robotics Lab, Advanced Robotics, Istituto Italiano di Tecnologia
Computer VisionBiomedical RoboticsBioengineering
N
Nazim Haouchine
Harvard Medical School, Brigham and Women’s Hospital, Boston, USA
Leonardo S. Mattos
Leonardo S. Mattos
Head of the Biomedical Robotics Lab at Istituto Italiano di Tecnologia
RoboticsAutomationMicrosurgeryMedical RoboticsMedical Image Analysis