Institution profile

Zhuhai College of Science and Technology

Academic institutionasia · cn
Official website
Research library4linked papers
Opportunities0open roles
Selected work

Representative Papers

Protein Structure Prediction: From Evolutionary Constraints to Generative Modeling

Aug 17, 2026

This study addresses the ambiguity surrounding the methodological evolution of protein structure prediction by proposing a "four-stage, three-transition" analytical framework. By systematically examining technical paradigm shifts across representation, architecture, and evaluation dimensions, this research integrates deep learning and generative modeling to elucidate the intrinsic trajectory from evolutionary constraints to generative design. Consequently, this work constructs a comprehensive methodological evolution map that clarifies historical transitions in model capabilities and application roles. Ultimately, it provides a systematic theoretical foundation for understanding the developmental logic and future trends within the field, offering critical insights into how predictive methodologies have matured over time.

0 citationsRead paper

Color Fundus Photography Analysis: Co-evolution of Data, Preprocessing, and Modeling toward Multimodal AI

Jul 26, 2026

Current AI research on color fundus photography (CFP) lacks a systematic perspective on the co-evolution of datasets, preprocessing, and modeling. This work proposes the first unified framework that synergistically optimizes data curation, preprocessing, and multimodal modeling, integrating neural data engineering, hardware-aware annotation, self-supervised electronic health record imputation, vision foundation models, state space models, and multimodal mixture-of-experts architectures. The study delineates a clear evolutionary trajectory for CFP analysis—from single-task convolutional neural networks toward multimodal, longitudinally integrated clinical systems—and provides a methodological roadmap toward robust ophthalmic AI capable of clinical deployment, cross-domain generalization, and edge intelligence.

0 citationsRead paper

Synergistic Foundation Models for Semi-Supervised Fetal Cardiac Ultrasound Analysis: SAM-Med2D Boundary Refinement and DINOv3 Semantic Enhancement

May 19, 2026

This study addresses the challenge of joint segmentation and classification in fetal echocardiography under severe label scarcity by proposing a semi-supervised multi-task learning framework. Built upon the EchoCare backbone, the method integrates SAM-Med2D for boundary refinement and leverages DINOv3 to enhance pseudo-label quality. A novel view-specific hard masking mechanism and a two-stage optimization strategy are introduced: the first stage employs exponential moving average (EMA) to boost segmentation performance, while the second stage freezes segmentation parameters and resets the classification head to restore discriminative capability. Evaluated on the FETUS 2026 benchmark, the model achieves a Dice coefficient of 79.99%, a normalized surface distance of 61.62%, and an F1 score of 41.20%, significantly outperforming existing approaches.

0 citationsRead paper
Recent publications

Latest Papers

Protein Structure Prediction: From Evolutionary Constraints to Generative Modeling

Aug 17, 2026

This study addresses the ambiguity surrounding the methodological evolution of protein structure prediction by proposing a "four-stage, three-transition" analytical framework. By systematically examining technical paradigm shifts across representation, architecture, and evaluation dimensions, this research integrates deep learning and generative modeling to elucidate the intrinsic trajectory from evolutionary constraints to generative design. Consequently, this work constructs a comprehensive methodological evolution map that clarifies historical transitions in model capabilities and application roles. Ultimately, it provides a systematic theoretical foundation for understanding the developmental logic and future trends within the field, offering critical insights into how predictive methodologies have matured over time.

0 citationsRead paper

Color Fundus Photography Analysis: Co-evolution of Data, Preprocessing, and Modeling toward Multimodal AI

Jul 26, 2026

Current AI research on color fundus photography (CFP) lacks a systematic perspective on the co-evolution of datasets, preprocessing, and modeling. This work proposes the first unified framework that synergistically optimizes data curation, preprocessing, and multimodal modeling, integrating neural data engineering, hardware-aware annotation, self-supervised electronic health record imputation, vision foundation models, state space models, and multimodal mixture-of-experts architectures. The study delineates a clear evolutionary trajectory for CFP analysis—from single-task convolutional neural networks toward multimodal, longitudinally integrated clinical systems—and provides a methodological roadmap toward robust ophthalmic AI capable of clinical deployment, cross-domain generalization, and edge intelligence.

0 citationsRead paper

Synergistic Foundation Models for Semi-Supervised Fetal Cardiac Ultrasound Analysis: SAM-Med2D Boundary Refinement and DINOv3 Semantic Enhancement

May 19, 2026

This study addresses the challenge of joint segmentation and classification in fetal echocardiography under severe label scarcity by proposing a semi-supervised multi-task learning framework. Built upon the EchoCare backbone, the method integrates SAM-Med2D for boundary refinement and leverages DINOv3 to enhance pseudo-label quality. A novel view-specific hard masking mechanism and a two-stage optimization strategy are introduced: the first stage employs exponential moving average (EMA) to boost segmentation performance, while the second stage freezes segmentation parameters and resets the classification head to restore discriminative capability. Evaluated on the FETUS 2026 benchmark, the model achieves a Dice coefficient of 79.99%, a normalized surface distance of 61.62%, and an F1 score of 41.20%, significantly outperforming existing approaches.

0 citationsRead paper