1. Ovchinnikova, K., Born, J., Chouvardas, P., Rapsomaniki, M. * and Kruithof de Julio, M.* (2024). 'Overcoming limitations in current measures of drug response may enable AI driven precision oncology.' npj Precision Oncology, 8, 95.
2. Gossi, F., Pati P., Chouvardas, P., Martinelli, A. L., Kruithof-de Julio, M., Rapsomaniki, M. A (2023). 'Matching single cells across modalities with contrastive learning and optimal transport.' Brief Bioinform 24(3).
3. Martinelli, A. L., Rapsomaniki, M. A (2022). 'ATHENA: analysis of tumor heterogeneity from spatial omics measurements.' Bioinformatics 38(11): 3151-3153.
4. Rapsomaniki, M. A., Maxouri, S., Nathanailidou, P., Garrastacho, M. R., Giakoumakis, N. N., Taraviras, S., Lygeros, J., Lygerou, Z. (2021). 'In silico analysis of DNA re-replication across a complete genome reveals cell-to-cell heterogeneity and genome plasticity.' NAR Genom Bioinform 3(1): lqaa112.
5. Wagner, J., Rapsomaniki, M. A., Chevrier, S., Anzeneder, T., Langwieder, C., Dykgers, A., Rees, M., Ramaswamy, A., Muenst, S., Soysal, S. D., Jacobs, A., Windhager, J., Silina, K., van den Broek, M., Dedes, K. J., Rodriguez Martinez, M., Weber, W. P., Bodenmiller, B. (2019). 'A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer.' Cell 177(5): 1330-1345 e1318.
6. Rapsomaniki, M. A., Lun, X. K., Woerner, S., Laumanns, M., Bodenmiller, B., Martinez, M. R. (2018). 'CellCycleTRACER accounts for cell cycle and volume in mass cytometry data.' Nat Commun 9(1): 632.
Research Experience
Tenure Track Assistant Professor, Research Lead, AI/ML for Biomedicine group leader
Background
Research interests include developing AI/ML approaches tailored to complex and multi-modal biomedical data to elucidate cancer mechanisms, from the intra-cellular to the patient level. Topics of special interest include understanding 3D genome regulation, modeling the tumor microenvironment using single-cell omics (transcriptomics, metabolomics, proteomics), and developing AI-driven precision oncology approaches based on predicting the effects of drug perturbations ex vivo.