Scholar
Abhishek Singharoy
Google Scholar ID: UnRHyFYAAAAJ
Associate professor
Citations & Impact
Citations
4,976
H-index
24
i10-index
42
Publications
20
Co-authors
0
Contact
No contact links provided.
Publications
Resume (English only)
Academic Achievements
- Published papers in journals such as Current Opinion in Structural Biology (2022, 73, 102338), Frontiers in Physiology (10, 46), Journal of Chemical Information and Modeling (2020, 60, 2591), Journal of Chemical Physics (2020, 153, 214102), Matter (2021, 4, 3195), Nature Communications (2020, 11, 4734), Science Advances (2020, 6, eabb9605), and Current Research in Structural Biology (2022, 4, 68); Developed methods including neural network potential-based flexible fitting, information theoretic approaches, and geometric machine learning; Introduced ManifoldEM technology to simultaneously track chemical reactions, structural transitions, and elastic deformations.
Research Experience
- Works at the School of Molecular Sciences (SMS) and Biodesign Institute (BDI) at Arizona State University (ASU), specifically within BDI’s Center for Applied Structural Discovery. The team, consisting of biophysicists, biochemists, and computer scientists, focuses on how energy transfer between hundreds of proteins embedded in cell membranes or the crowded interiors of cells affects phenotypic outcomes (such as light adaptations, growth, and immunogenicity), the oligomeric architecture and 'chemomechanical coupling' of mitochondrial protein complexes and rotatory F-/V-/A-type ATPases, and how leakage in these energy networks leads to aging and health disorders like cancer and neurodegenerative diseases.
Background
- Research Interests: The molecular origins of life; Fields include biophysics, biochemistry, and computer science; Aims to explore the design principles of life by determining the structures of biomolecules.
Co-authors