Giovanni Stracquadanio
Scholar

Giovanni Stracquadanio

Google Scholar ID: MiP4VoYAAAAJ
Personal Chair in Engineering Biology, The University of Edinburgh
Synthetic BiologyComputational BiologyAILysosomal Storage DiseasesCancer Genetics
Citations & Impact
All-time
Citations
2,362
 
H-index
21
 
i10-index
29
 
Publications
20
 
Co-authors
14
list available
Resume (English only)
Academic Achievements
  • - APEX: Automated Protein EXpression in Escherichia coli. ACS Synthetic Biology, 2025.
  • - Protein engineering using variational free energy approximation. Nature Communications, 2024.
  • - Dirichlet latent modelling enables effective learning and sampling of the functional protein design space. Nature Communications, 2024.
  • - Synthetic genome modules designed for programmable silencing of functions and chromosomes. bioRxiv, 2024.
  • - Beyond the marrow: insights from comprehensive next-generation sequencing of extramedullary multiple myeloma tumors. Leukemia, 2024.
  • - Biofoundry-Scale DNA Assembly Validation Using Cost-Effective High-Throughput Long-Read Sequencing. ACS Synthetic Biology, 2024.
  • - Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions. Cell, 2023.
  • - Manipulating the 3D organization of the largest synthetic yeast chromosome. Molecular Cell, 2023.
  • - Parallel laboratory evolution and rational debugging reveal genomic plasticity to S. cerevisiae synthetic chromosome XIV defects. Cell Genomics, 2023.
  • - Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains. Cell Genomics, 2023.
Research Experience
  • Leads a multidisciplinary research group at the School of Biological Sciences, University of Edinburgh, focusing on the development of new therapies for rare diseases.
Background
  • Research interests include developing highly effective therapies using AI and engineering biology, particularly for Lysosomal Storage Diseases (LSDs), such as Fabry disease.
Miscellany
  • Appointed as Deputy Director of the Centre for Engineering Biology; Involved in several academic conference presentations.