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Academic Achievements
Secured funding from NIH, Chao Foundation, Dunn Foundation, DOD, CPRIT, Tina’s Wish Foundation, and others
Key grants include NIH R01CA238727 (brain metastasis and Alzheimer’s suppression), NIH R01CA177909 (platelets in ovarian cancer), and NIH U01CA253553 (spatiotemporal modeling of bone metastasis)
Developed a novel PCDH7 single-domain antibody therapy for brain metastases
Repurposed digoxin for Group III/IV medulloblastoma, advancing to clinical trial
Identified prognostic genes in glioblastoma and biomarkers in high-grade serous ovarian cancer
Research Experience
Affiliated with the Systems Medicine and Bioengineering (SMAB) program at Houston Methodist Academic Institute
Integrates bioengineering with systems medicine to understand disease mechanisms, particularly in cancer, neurological, and metabolic disorders
Leads research projects on brain tumors, ovarian cancer, lung disease, bone cancer, and breast cancer
Research includes tumor-astrocyte crosstalk, single-domain antibody therapeutics, drug repositioning, exosomal communication, immunotherapy, platelet-tumor interactions, and immuno-radiotherapy crosstalk