🤖 AI Summary
To address data silos and privacy concerns in multi-center cancer research, this paper proposes the first distributed Fuzzy Cognitive Map (FCM) learning framework integrating Secure Multi-Party Computation (SMPC) and Differential Privacy (DP). Built upon a federated learning architecture and distributed optimization, the method enables cross-institutional collaborative modeling without sharing raw patient data, while supporting interpretable causal inference. Its key innovation lies in the first incorporation of FCMs into a privacy-enhancing distributed learning paradigm—uniquely preserving model interpretability alongside strong formal privacy guarantees. Extensive experiments on multiple real-world cancer datasets demonstrate that the proposed approach achieves accuracy comparable to centralized training, while reducing data leakage risk by 99.7%. This substantially improves both practical feasibility and regulatory compliance for collaborative oncology research across healthcare institutions.