Taming foundation model with invariance-oriented pre-training for broad-spectrum EEG analysis across signal-level, brain-state, and brain-health tasks

📅 2026-08-25
📈 Citations: 0
Influential: 0
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🤖 AI Summary
研究通过使用INCEPT模型,采用不变性导向的预训练方法解决EEG分析中跨信号级、脑状态和脑健康任务的泛化问题。
📝 Abstract
Electroencephalography (EEG) is a widely used window into human brain function, but most EEG models remain tied to a one-dataset-one-model supervised paradigm. Recent EEG foundation models offer a route toward reusable representations, but most remain reconstruction-centered, assuming that EEG content predictable from local context is necessarily transferable neural information. Here we present INCEPT, an invariance-oriented EEG foundation model trained on over 11,000 hours of unlabelled clinical EEG. Rather than prioritizing signal recovery alone, INCEPT learns representation-level stability across correlated EEG observations, separating stable neural structure and essential subject-sensitive information from the nuisance variability that dominates scalp recordings while preserving subject-, state- and condition-discriminative information. We evaluate INCEPT on a broad-spectrum benchmark of ten datasets spanning three levels of post-acquisition EEG analysis: signal-level assessment, brain-state decoding, and brain-health evaluation. INCEPT ranks first among recent EEG foundation models on 26 of 30 linear-probing metrics and 24 of 30 fine-tuning metrics, and also surpasses strong task-specific specialist encoders across diverse downstream settings. Objective ablations and representation analyses further show that invariance-oriented pre-training improves transfer and organizes subject-sensitive neural representations beyond reconstruction alone. These results establish invariance learning as a promising principle for building reusable EEG foundation models.
Problem

Research questions and friction points this paper is trying to address.

EEG
invariance
transferability
foundation model
broad-spectrum analysis
Innovation

Methods, ideas, or system contributions that make the work stand out.

invariance-oriented pre-training
EEG foundation model
representation-level stability
Y
Yulong Dou
School of Biomedical Engineering & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, 201210, China.
Han Wu
Han Wu
Shanghaitech University
Medical Image Analysis
G
Guo Chen
School of Biomedical Engineering & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, 201210, China.
F
Fangmao Ju
School of Biomedical Engineering & State Key Laboratory of Advanced Medical Materials and Devices, ShanghaiTech University, Shanghai, 201210, China.
Zhiming Cui
Zhiming Cui
ShanghaiTech University
Medical Image ComputingGenAI in Medical ImagingDigital Dentistry
Dinggang Shen
Dinggang Shen
Prof. and Founding Dean, School of BME, ShanghaiTech University; Co-CEO, United Imaging Intelligence
Medical Image AnalysisMedical Image ComputingBiomedical Image AnalysisImage Registration