VasGuideNet: Vascular Topology-Guided Couinaud Liver Segmentation with Structural Contrastive Loss

๐Ÿ“… 2026-02-24
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Existing Couinaud liver segmentation methods often yield ambiguous boundaries and exhibit limited generalization under anatomical variations due to their neglect of vascular topology. To address this, this work proposes VasGuideNet, the first framework to explicitly integrate vascular topology into the segmentation process. It employs a graph convolutional network to model the geometric and connectivity characteristics of the vascular skeleton and fuses this information into a 3D encoderโ€“decoder architecture via a cross-attention mechanism. Additionally, a structural contrastive loss and a global memory bank are introduced to enhance anatomical consistency and inter-class separability. Evaluated on the Task08_HepaticVessel and LASSD datasets, VasGuideNet achieves Dice scores of 83.68% and 76.65%, with relative volume differences (RVD) of 1.68 and 7.08, respectively, outperforming baseline models such as UNETR and Swin UNETR.

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๐Ÿ“ Abstract
Accurate Couinaud liver segmentation is critical for preoperative surgical planning and tumor localization.However, existing methods primarily rely on image intensity and spatial location cues, without explicitly modeling vascular topology. As a result, they often produce indistinct boundaries near vessels and show limited generalization under anatomical variability.We propose VasGuideNet, the first Couinaud segmentation framework explicitly guided by vascular topology. Specifically, skeletonized vessels, Euclidean distance transform (EDT)--derived geometry, and k-nearest neighbor (kNN) connectivity are encoded into topology features using Graph Convolutional Networks (GCNs). These features are then injected into a 3D encoder--decoder backbone via a cross-attention fusion module. To further improve inter-class separability and anatomical consistency, we introduce a Structural Contrastive Loss (SCL) with a global memory bank.On Task08_HepaticVessel and our private LASSD dataset, VasGuideNet achieves Dice scores of 83.68% and 76.65% with RVDs of 1.68 and 7.08, respectively. It consistently outperforms representative baselines including UNETR, Swin UNETR, and G-UNETR++, delivering higher Dice/mIoU and lower RVD across datasets, demonstrating its effectiveness for anatomically consistent segmentation. Code is available at https://github.com/Qacket/VasGuideNet.git.
Problem

Research questions and friction points this paper is trying to address.

Couinaud segmentation
vascular topology
anatomical variability
boundary ambiguity
liver segmentation
Innovation

Methods, ideas, or system contributions that make the work stand out.

vascular topology
Graph Convolutional Networks
Structural Contrastive Loss
Couinaud segmentation
cross-attention fusion
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