Gaussian surrogates do well on Poisson inverse problems

📅 2026-02-19
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This study addresses the inconsistency between objective functions and performance metrics in inverse imaging problems under Poisson noise, where methods typically optimize Poisson likelihood yet are evaluated using mean squared error (MSE). The authors systematically investigate the MSE performance of Gaussian surrogate objectives—both homoscedastic and heteroscedastic quadratic forms—in low-dose settings, comparing them against Poisson maximum likelihood estimation (MLE) and maximum a posteriori (MAP) approaches. By leveraging theoretical analysis within a diagonalized model, they derive closed-form MSE expressions for four representative methods and validate their findings through CT reconstruction experiments. The results demonstrate that, even at low doses, simple Gaussian surrogates can achieve MSE performance comparable to regularized Poisson MAP while offering significantly higher computational efficiency, thereby challenging the prevailing paradigm that Poisson likelihood is indispensable for accurate low-dose reconstruction.

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📝 Abstract
In imaging inverse problems with Poisson-distributed measurements, it is common to use objectives derived from the Poisson likelihood. But performance is often evaluated by mean squared error (MSE), which raises a practical question: how much does a Poisson objective matter for MSE, even at low dose? We analyze the MSE of Poisson and Gaussian surrogate reconstruction objectives under Poisson noise. In a stylized diagonal model, we show that the unregularized Poisson maximum-likelihood estimator can incur large MSE at low dose, while Poisson MAP mitigates this instability through regularization. We then study two Gaussian surrogate objectives: a heteroscedastic quadratic objective motivated by the normal approximation of Poisson data, and a homoscedastic quadratic objective that yields a simple linear estimator. We show that both surrogates can achieve MSE comparable to Poisson MAP in the low-dose regime, despite departing from the Poisson likelihood. Numerical computed tomography experiments indicate that these conclusions extend beyond the stylized setting of our theoretical analysis.
Problem

Research questions and friction points this paper is trying to address.

Poisson inverse problems
mean squared error
Gaussian surrogates
low-dose imaging
reconstruction objectives
Innovation

Methods, ideas, or system contributions that make the work stand out.

Poisson inverse problems
Gaussian surrogate
mean squared error
low-dose imaging
maximum a posteriori estimation
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A
Alexandra Spitzer
Department of Mathematics and Computer Science, University of Basel, 4051 Basel, Switzerland
L
Lorenzo Baldassari
Department of Mathematics and Computer Science, University of Basel, 4051 Basel, Switzerland
V
Valentin Derbanot
INSA-Lyon, Universite Claude Bernard Lyon 1, CNRS, Inserm, CREATIS UMR 5220, U1294
Ivan Dokmanić
Ivan Dokmanić
Associate Professor, Department of Mathematics and Computer Science, University of Basel
Signal ProcessingMachine LearningInverse Problems