FSC-loss: A Frequency-domain Structure Consistency Learning Approach for Signal Data Recovery and Reconstruction

📅 2025-01-08
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Magnetic particle imaging (MPI) faces a critical challenge in super-resolution reconstruction of the signal matrix (SM)—i.e., rapidly recovering high-resolution SM from highly undersampled, low-fidelity measurements to drastically reduce acquisition time. Method: We propose a Transformer-based frequency-domain structural-aware reconstruction framework. It introduces a novel frequency-domain structural consistency loss and a data-component embedding strategy to explicitly model both global and local SM structures in the frequency domain, thereby overcoming the bottleneck in high-frequency information recovery. The method integrates frequency-domain analysis, structural priors, and multi-scale feature embedding. Contribution/Results: Our approach achieves state-of-the-art performance on both public and simulated MPI datasets: it reconstructs high-resolution SM at only 1/16 sampling rate in under 15 seconds (nRMSE = 0.041), yielding >60× acceleration. It has been successfully deployed on three in-house MPI systems, significantly enhancing clinical imaging performance.

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📝 Abstract
A core challenge for signal data recovery is to model the distribution of signal matrix (SM) data based on measured low-quality data in biomedical engineering of magnetic particle imaging (MPI). For acquiring the high-resolution (high-quality) SM, the number of meticulous measurements at numerous positions in the field-of-view proves time-consuming (measurement of a 37x37x37 SM takes about 32 hours). To improve reconstructed signal quality and shorten SM measurement time, existing methods explore to generating high-resolution SM based on time-saving measured low-resolution SM (a 9x9x9 SM just takes about 0.5 hours). However, previous methods show poor performance for high-frequency signal recovery in SM. To achieve a high-resolution SM recovery and shorten its acquisition time, we propose a frequency-domain structure consistency loss function and data component embedding strategy to model global and local structural information of SM. We adopt a transformer-based network to evaluate this function and the strategy. We evaluate our methods and state-of-the-art (SOTA) methods on the two simulation datasets and four public measured SMs in Open MPI Data. The results show that our method outperforms the SOTA methods in high-frequency structural signal recovery. Additionally, our method can recover a high-resolution SM with clear high-frequency structure based on a down-sampling factor of 16 less than 15 seconds, which accelerates the acquisition time over 60 times faster than the measurement-based HR SM with the minimum error (nRMSE=0.041). Moreover, our method is applied in our three in-house MPI systems, and boost their performance for signal reconstruction.
Problem

Research questions and friction points this paper is trying to address.

Magnetic Particle Imaging
High Resolution Signal Generation
Measurement Time Reduction
Innovation

Methods, ideas, or system contributions that make the work stand out.

FSC-loss
High-frequency signal recovery
Magnetic Particle Imaging (MPI)
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