AutoIQ: An Ensemble Framework for Automatic Assessment of Geometric Distortion in Prostate Diffusion-Weighted Imaging

📅 2026-05-29
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🤖 AI Summary
Geometric distortions in prostate diffusion-weighted imaging (DWI) significantly compromise lesion localization and clinical assessment, necessitating automated quality control. To address this challenge, this work proposes AutoIQ, a novel framework that integrates two complementary strategies: a segmentation-based metric quantifying prostate boundary mismatch and a registration-based estimation of deformation magnitude. These features are combined via logistic regression to construct a classifier capable of fully automatic quantification and classification of DWI geometric distortion severity. Evaluated on an independent test set, AutoIQ achieves 95% accuracy, an F1 score of 0.93, and an AUC of 0.98, substantially outperforming single-strategy models. The method demonstrates high efficacy in identifying severely distorted images requiring rescanning, offering a robust solution for clinical quality assurance.
📝 Abstract
Geometric distortion in prostate diffusion-weighted imaging (DWI) can impair lesion localization and reduce the reliability of MRI-based clinical assessment. We propose AutoIQ, an ensemble machine learning framework for automatic quantification and classification of DWI geometric distortion severity. A total of 140 retrospective prostate biparametric MRI examinations were analyzed, including 33 scans with severe distortion requiring repeat acquisition and 107 scans with acceptable distortion based on expert radiologist assessment. AutoIQ combines two complementary distortion quantification strategies: a segmentation-based method measuring prostate boundary mismatch between T2-weighted imaging (T2WI) and DWI, and a registration-based method estimating deformation magnitude after DWI-to-T2WI alignment. The resulting distortion scores were used to train individual classifiers and a logistic-regression ensemble model. Both computational methods significantly differentiated severe from acceptable distortion cases (p < 0.001). On an independent test set, the ensemble model achieved an accuracy of 0.95, F1-score of 0.93, and AUC of 0.98, outperforming individual models. These results suggest that AutoIQ can provide automated, quantitative quality assessment for prostate DWI and may help identify scans that require repeat acquisition.
Problem

Research questions and friction points this paper is trying to address.

geometric distortion
prostate diffusion-weighted imaging
image quality assessment
lesion localization
MRI
Innovation

Methods, ideas, or system contributions that make the work stand out.

ensemble learning
geometric distortion
prostate MRI
diffusion-weighted imaging
image registration
H
Haoran Sun
Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Bioengineering, University of California, Los Angeles, CA, USA
L
Lixia Wang
Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
Y
Yin-Chen Hsu
Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
H
Hsu-Lei Lee
Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
Chang Gao
Chang Gao
Siemens Healthineers
deep learningmedical imagingmagnetic resonance imaging
Fei Han
Fei Han
Siemens Healthineers
Medical ImagingMagnetic Resonance Imaging
Robert Grimm
Robert Grimm
Computational Linguistics and Psycholinguistics Research Center, University of Antwerp
V
Vibhas Deshpande
Siemens Medical Solutions USA Inc., Austin, TX, USA
Z
Ziyang Long
Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Bioengineering, University of California, Los Angeles, CA, USA
H
Hsin-Jung Yang
Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA
R
Rola Saouaf
Department of Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, USA
A
Alessandro D'Agnolo
Department of Nuclear Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA
T
Timothy Daskivich
Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA
H
Hyung Kim
Department of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA
D
Debiao Li
Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA; Department of Bioengineering, University of California, Los Angeles, CA, USA
Yibin Xie
Yibin Xie
Cedars-Sinai Medical Center
Medical ImagingCardiovascular BiologyMagnetic Resonance