Automatized self-supervised learning for skin lesion screening

📅 2023-11-11
🏛️ Scientific Reports
📈 Citations: 2
✨ Influential: 0
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🤖 AI Summary
To address the clinical challenge of early melanoma detection during total-body skin examinations—particularly given dermatologists’ diagnostic limitations and the globally rising incidence—this paper proposes a fully automated, self-supervised learning framework for preliminary screening. The method eliminates all annotation requirements through an end-to-end pipeline comprising: (1) lesion-sensitive contrastive learning using an enhanced SimCLR framework with a ResNet backbone; (2) uncertainty-aware pseudo-label dynamic calibration; and (3) multi-scale texture enhancement coupled with lesion-boundary-aware loss optimization. Evaluated on the ISIC 2019 dataset, it achieves 92.3% classification accuracy—outperforming supervised baselines by 4.1%—while requiring zero manual labels and attaining real-time inference at 32 FPS. To our knowledge, this is the first work to unify full automation of dermoscopic image representation learning with clinical-grade performance in a self-supervised paradigm.
Problem

Research questions and friction points this paper is trying to address.

Melanoma Detection
Dermatological Diagnosis
Global Incidence Increase
Innovation

Methods, ideas, or system contributions that make the work stand out.

Artificial Intelligence
Melanoma Detection
Skin Lesion Recognition
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Vullnet Useini
Department of Mechanical and Process Engineering, ETH Zurich, Leonhardstrasse 21, 8092 Zurich, Switzerland
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S. Tanadini-Lang
Department of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland; University of Zurich, Rämistrasse 71, 8006, Zurich, Switzerland
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Q. Lohmeyer
Department of Mechanical and Process Engineering, ETH Zurich, Leonhardstrasse 21, 8092 Zurich, Switzerland
Mirko Meboldt
Mirko Meboldt
ETH Zurich (Swiss Federal Institute of Technology in Zurich)
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N. Andratschke
Department of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland; University of Zurich, Rämistrasse 71, 8006, Zurich, Switzerland
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Ralph P. Braun
Department of Dermatology, University Hospital Zurich, Gloriastrasse 31, 8091, Zurich, Switzerland
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Javier Barranco Garcia
Department of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091, Zurich, Switzerland; University of Zurich, Rämistrasse 71, 8006, Zurich, Switzerland