HeartVolMesh: Cardiac Volumetric Mesh Reconstruction via Covariance-Guided Graph Deformation

📅 2026-07-05
📈 Citations: 0
Influential: 0
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🤖 AI Summary
Existing segmentation-to-mesh approaches struggle to accurately reconstruct thin cardiac walls and lack consistent anatomical correspondence across subjects. To address these limitations, this work proposes a template-driven, high-fidelity tetrahedral mesh reconstruction method. The approach models template vertices as anisotropic Gaussian kernels and employs a joint 3D CNN–GNN architecture to predict vertex displacements and covariances—parameterized via Cholesky decomposition. A covariance-guided graph deformation mechanism is introduced to refine mesh geometry while preserving both topological integrity and cross-subject correspondence, substantially improving thin-wall reconstruction accuracy. By integrating staged alignment, non-rigid registration, and deformation propagation strategies, the method outperforms existing deformation-based models in both surface and volumetric mesh quality, enabling more precise patient-specific cardiac modeling.
📝 Abstract
Accurate patient-specific tetrahedral cardiac meshes are essential for in-silico trials, yet common segmentation-then-modelling pipelines can blur thin-wall anatomy and offer limited cross-case correspondence. We propose HeartVolMesh, which lifts each template vertex to an anisotropic Gaussian kernel and uses a 3D CNN-GNN to predict per-vertex displacements and Cholesky-parameterized covariances from volumetric images. Training is guided by a covariance-aware negative log-likelihood loss with lightweight mesh regularization. For volumetric meshing, we warp a fixed tetrahedral template to the reconstructed surface via staged alignment, non-rigid registration, and deformation propagation, preserving connectivity and correspondence by construction, with resolution controlled by template density. Experiments show consistent gains over deformation-based baselines in surface mesh accuracy and volumetric mesh fidelity.
Problem

Research questions and friction points this paper is trying to address.

cardiac mesh reconstruction
patient-specific modeling
volumetric meshing
thin-wall anatomy
cross-case correspondence
Innovation

Methods, ideas, or system contributions that make the work stand out.

covariance-guided deformation
tetrahedral mesh reconstruction
3D CNN-GNN
anisotropic Gaussian kernel
patient-specific cardiac modeling
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Fengming Lin
Centre for Computational Imaging and Modelling in Medicine (CIMIM), University of Manchester, Manchester, UK; Christabel Pankhurst Institute, University of Manchester, Manchester, UK; Department of Computer Science, University of Manchester, Manchester, UK
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Arezoo Zakeri
Centre for Computational Imaging and Modelling in Medicine (CIMIM), University of Manchester, Manchester, UK; Christabel Pankhurst Institute, University of Manchester, Manchester, UK; Division of Informatics, Imaging & Data Sciences, University of Manchester, Manchester, UK
Haoran Dou
Haoran Dou
Research Associate, The University of Manchester
Medical Image AnalysisIn-silico Trials
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Zherui Zhou
Centre for Computational Imaging and Modelling in Medicine (CIMIM), University of Manchester, Manchester, UK; Christabel Pankhurst Institute, University of Manchester, Manchester, UK
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Shaokun Lan
Centre for Computational Imaging and Modelling in Medicine (CIMIM), University of Manchester, Manchester, UK; Christabel Pankhurst Institute, University of Manchester, Manchester, UK; Department of Computer Science, University of Manchester, Manchester, UK
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Jinming Duan
Centre for Computational Imaging and Modelling in Medicine (CIMIM), University of Manchester, Manchester, UK; Christabel Pankhurst Institute, University of Manchester, Manchester, UK; Division of Informatics, Imaging & Data Sciences, University of Manchester, Manchester, UK
A
Alejandro Frangi
Centre for Computational Imaging and Modelling in Medicine (CIMIM), University of Manchester, Manchester, UK; Christabel Pankhurst Institute, University of Manchester, Manchester, UK; Department of Computer Science, University of Manchester, Manchester, UK; Division of Informatics, Imaging & Data Sciences, University of Manchester, Manchester, UK; NIHR Manchester Biomedical Research Centre, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK