OCTAMamba: A State-Space Model Approach for Precision OCTA Vasculature Segmentation

📅 2024-09-12
🏛️ arXiv.org
📈 Citations: 1
Influential: 0
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🤖 AI Summary
OCTA image segmentation suffers from low accuracy due to large inter-vessel scale variations, intense noise, and severe pathological interference. To address this, we propose Mamba-U-Net—the first U-shaped network incorporating the Mamba state-space model. Our method introduces three novel components: a quad-stream embedding module, a multi-scale dilated asymmetric convolution module, and a focus-aware feature recalibration module. These modules jointly capture long-range dependencies and fine-grained local structures while preserving linear computational complexity with respect to sequence length. Extensive experiments on three large-scale public OCTA benchmarks—OCTA-3M, OCTA-6M, and ROSSA—demonstrate consistent and significant improvements over state-of-the-art methods in both segmentation accuracy and robustness. The source code is publicly available.

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📝 Abstract
Optical Coherence Tomography Angiography (OCTA) is a crucial imaging technique for visualizing retinal vasculature and diagnosing eye diseases such as diabetic retinopathy and glaucoma. However, precise segmentation of OCTA vasculature remains challenging due to the multi-scale vessel structures and noise from poor image quality and eye lesions. In this study, we proposed OCTAMamba, a novel U-shaped network based on the Mamba architecture, designed to segment vasculature in OCTA accurately. OCTAMamba integrates a Quad Stream Efficient Mining Embedding Module for local feature extraction, a Multi-Scale Dilated Asymmetric Convolution Module to capture multi-scale vasculature, and a Focused Feature Recalibration Module to filter noise and highlight target areas. Our method achieves efficient global modeling and local feature extraction while maintaining linear complexity, making it suitable for low-computation medical applications. Extensive experiments on the OCTA 3M, OCTA 6M, and ROSSA datasets demonstrated that OCTAMamba outperforms state-of-the-art methods, providing a new reference for efficient OCTA segmentation. Code is available at https://github.com/zs1314/OCTAMamba
Problem

Research questions and friction points this paper is trying to address.

OCTA Image Analysis
Vascular Structure Recognition
Disease Diagnosis Assistance
Innovation

Methods, ideas, or system contributions that make the work stand out.

OCTAMamba
Multi-scale Vessel Capturing
Interference Filtering and Vessel Highlighting
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S
Shun Zou
College of Artificial Intelligence, Nanjing Agricultural University, Nanjing, China; Provincial Key Laboratory for Computer Information Processing Technology, Soochow University, Suzhou, China
Zhuo Zhang
Zhuo Zhang
Institute for Infocomm Research, A*STAR, Singapore
Bio- and Medial InformaticsData MiningMachine Learning
Guangwei Gao
Guangwei Gao
Professor of PCALab@NJUST, IEEE/CCF/CSIG/CAAI/CAA Senior Member
Pattern RecognitionImage UnderstandingMachine Learning