Image-Conditioned Diffusion Models for Quality Assurance of Organ-at-Risk Segmentations in Radiotherapy

📅 2026-08-24
📈 Citations: 0
Influential: 0
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🤖 AI Summary
研究使用图像条件扩散模型来检测头颈部CT中器官风险分割的错误,以提高放射治疗规划的质量保证。
📝 Abstract
Accurate organ-at-risk segmentation is essential for radiotherapy planning, but reviewing segmentations is time-consuming and subjective. We investigate normative modelling for segmentation error detection in head-and-neck CT, comparing a VAE framework with an image-conditioned segmentation diffusion model. Models were evaluated on RADCURE brainstem and spinal cord segmentations using simulated boundary and width perturbations. Error detection was assessed using the Dice similarity coefficient and the Distance to Agreement (DTA) between the input and reconstructed segmentations. While both models detected some simulated errors, regional DTA showed that the diffusion model localised subtle boundary errors more consistently. These results support image-conditioned diffusion reconstruction as a promising framework for localised, anatomy-aware segmentation QA.
Problem

Research questions and friction points this paper is trying to address.

segmentation
radiotherapy
error detection
image-conditioned
Innovation

Methods, ideas, or system contributions that make the work stand out.

Image-Conditioned Diffusion Model
Segmentation Quality Assurance
Anatomy-Aware
Error Detection
Head-and-Neck CT
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