Fast and Robust Likelihood-Guided Diffusion Posterior Sampling with Amortized Variational Inference

📅 2026-02-06
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🤖 AI Summary
This work addresses the high computational cost of zero-shot posterior sampling in diffusion models for inverse problems and the limited generalization of existing amortized methods to unseen degradation operators. The authors propose a variational inference–based amortization strategy that explicitly models likelihood guidance and amortizes the inner optimization loop, thereby significantly accelerating inference while preserving the flexibility of zero-shot approaches. By uniquely integrating amortized inference with explicit likelihood guidance, the method achieves efficient reconstruction on in-distribution degradations and demonstrates remarkable robustness and reconstruction quality under out-of-distribution or previously unseen degradation operators, consistently outperforming both current amortized and zero-shot baselines.

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📝 Abstract
Zero-shot diffusion posterior sampling offers a flexible framework for inverse problems by accommodating arbitrary degradation operators at test time, but incurs high computational cost due to repeated likelihood-guided updates. In contrast, previous amortized diffusion approaches enable fast inference by replacing likelihood-based sampling with implicit inference models, but at the expense of robustness to unseen degradations. We introduce an amortization strategy for diffusion posterior sampling that preserves explicit likelihood guidance by amortizing the inner optimization problems arising in variational diffusion posterior sampling. This accelerates inference for in-distribution degradations while maintaining robustness to previously unseen operators, thereby improving the trade-off between efficiency and flexibility in diffusion-based inverse problems.
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Research questions and friction points this paper is trying to address.

diffusion posterior sampling
inverse problems
amortized inference
likelihood guidance
robustness
Innovation

Methods, ideas, or system contributions that make the work stand out.

amortized variational inference
likelihood-guided diffusion
posterior sampling
inverse problems
zero-shot generalization
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