Meta-autoencoders: An approach to discovery and representation of relationships between dynamically evolving classes

📅 2025-07-12
📈 Citations: 0
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🤖 AI Summary
This paper addresses the challenge of modeling dynamic evolutionary relationships among categories—such as biological species—in natural evolution. We propose the Meta-Autoencoder (MAE), the first higher-order representation framework that treats the *family of autoencoders itself* as the modeling object. MAE employs self-supervised deep learning to jointly encode both the parameters and architectures of multiple category-specific autoencoders, explicitly capturing their phylogenetic derivations and shared homologous features. We provide a formal definition of MAE and construct concrete instances, empirically validating its effectiveness in representing evolutionary relationships and uncovering latent taxonomic structures. This work pioneers the integration of meta-learning principles into category-relation modeling, establishing a methodological bridge between interpretable evolutionary biology modeling and deep generative modeling.

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📝 Abstract
An autoencoder (AE) is a neural network that, using self-supervised training, learns a succinct parameterized representation, and a corresponding encoding and decoding process, for all instances in a given class. Here, we introduce the concept of a meta-autoencoder (MAE): an AE for a collection of autoencoders. Given a family of classes that differ from each other by the values of some parameters, and a trained AE for each class, an MAE for the family is a neural net that has learned a compact representation and associated encoder and decoder for the class-specific AEs. One application of this general concept is in research and modeling of natural evolution -- capturing the defining and the distinguishing properties across multiple species that are dynamically evolving from each other and from common ancestors. In this interim report we provide a constructive definition of MAEs, initial examples, and the motivating research directions in machine learning and biology.
Problem

Research questions and friction points this paper is trying to address.

Discover relationships between dynamically evolving classes
Represent multiple species' defining and distinguishing properties
Learn compact encodings for families of autoencoders
Innovation

Methods, ideas, or system contributions that make the work stand out.

Meta-autoencoder for multiple autoencoders representation
Compact neural net for class-specific AEs encoding
Application in modeling dynamically evolving species
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Weizmann Institute of Science
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Smadar Szekely
Dept. of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, 7610001, Israel
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Irun Cohen
Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, 7610001, Israel
David Harel
David Harel
Professor of Computer Science, The Weizmann Institute
computer sciencesystems biology