SurvKAN: A Fully Parametric Survival Model Based on Kolmogorov-Arnold Networks

📅 2026-02-02
📈 Citations: 0
Influential: 0
📄 PDF
🤖 AI Summary
This work proposes SurvKAN, a fully parametric, time-continuous survival model based on Kolmogorov–Arnold Networks (KANs), which overcomes the limitations of traditional survival models—such as the Cox proportional hazards model—that rely on linear assumptions and proportional hazards constraints. Unlike existing deep learning approaches that sacrifice interpretability for flexibility, SurvKAN explicitly incorporates time as an input and directly models the log-hazard function, optimizing the full survival likelihood via end-to-end maximum likelihood estimation. By introducing the KAN architecture to survival analysis for the first time, the method dispenses with the proportional hazards assumption while achieving concordance indices and calibration performance on par with or superior to state-of-the-art methods across standard benchmarks. Moreover, it offers feature-level interpretability through learnable univariate functions, revealing risk patterns consistent with medical priors.

Technology Category

Application Category

📝 Abstract
Accurate prediction of time-to-event outcomes is critical for clinical decision-making, treatment planning, and resource allocation in modern healthcare. While classical survival models such as Cox remain widely adopted in standard practice, they rely on restrictive assumptions, including linear covariate relationships and proportional hazards over time, that often fail to capture real-world clinical dynamics. Recent deep learning approaches like DeepSurv and DeepHit offer improved expressivity but sacrifice interpretability, limiting clinical adoption where trust and transparency are paramount. Hybrid models incorporating Kolmogorov-Arnold Networks (KANs), such as CoxKAN, have begun to address this trade-off but remain constrained by the semi-parametric Cox framework. In this work we introduce SurvKAN, a fully parametric, time-continuous survival model based on KAN architectures that eliminates the proportional hazards constraint. SurvKAN treats time as an explicit input to a KAN that directly predicts the log-hazard function, enabling end-to-end training on the full survival likelihood. Our architecture preserves interpretability through learnable univariate functions that indicate how individual features influence risk over time. Extensive experiments on standard survival benchmarks demonstrate that SurvKAN achieves competitive or superior performance compared to classical and state-of-the-art baselines across concordance and calibration metrics. Additionally, interpretability analyses reveal clinically meaningful patterns that align with medical domain knowledge.
Problem

Research questions and friction points this paper is trying to address.

survival analysis
time-to-event prediction
proportional hazards
model interpretability
clinical decision-making
Innovation

Methods, ideas, or system contributions that make the work stand out.

Survival analysis
Kolmogorov-Arnold Networks
Fully parametric model
Interpretability
Time-to-event prediction
🔎 Similar Papers
No similar papers found.
M
Marina Mastroleo
Department of Electronics, Information, and Bioengineering, Politecnico di Milano, Milan, Italy
Alberto Archetti
Alberto Archetti
Postdoctoral Researcher, Politecnico di Milano
Survival AnalysisFederated LearningArtificial Life
F
Federico Mastroleo
Department of Radiation Oncology, Mayo Clinic, Rochester, MN, United States; Division of Radiation Oncology, IEO, European Institute of Oncology, IRCCS, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
Matteo Matteucci
Matteo Matteucci
Full Professor, Department of Electronics Information and Bioengineering, Politecnico di Milano
RoboticsMachine LearningComputer VisionPattern Recognition