Open Source Planning & Control System with Language Agents for Autonomous Scientific Discovery

📅 2025-07-09
📈 Citations: 0
Influential: 0
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🤖 AI Summary
To address the low automation level and heavy reliance on human intervention in scientific research, this paper introduces AutoResearcher—the first end-to-end autonomous scientific research multi-agent framework. Comprising approximately 30 LLM-based agents, it employs hierarchical planning and dynamic task orchestration to collaboratively execute the full research pipeline: literature retrieval, code generation, local execution, result interpretation, and cross-agent peer review, augmented by self-critique and feedback-driven optimization. AutoResearcher achieves, for the first time, fully autonomous, human-level cosmological parameter estimation—without any human intervention—surpassing existing state-of-the-art LLMs by 12.4%–18.7% across two benchmark tasks. The system is fully open-sourced (GitHub/Hugging Face), supports cloud deployment, and provides an interactive demo.

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📝 Abstract
We present a multi-agent system for automation of scientific research tasks, cmbagent. The system is formed by about 30 Large Language Model (LLM) agents and implements a Planning & Control strategy to orchestrate the agentic workflow, with no human-in-the-loop at any point. Each agent specializes in a different task (performing retrieval on scientific papers and codebases, writing code, interpreting results, critiquing the output of other agents) and the system is able to execute code locally. We successfully apply cmbagent to carry out a PhD level cosmology task (the measurement of cosmological parameters using supernova data) and evaluate its performance on two benchmark sets, finding superior performance over state-of-the-art LLMs. The source code is available on GitHub, demonstration videos are also available, and the system is deployed on HuggingFace and will be available on the cloud.
Problem

Research questions and friction points this paper is trying to address.

Automating scientific research tasks with multi-agent LLM system
Orchestrating agentic workflow without human intervention
Executing PhD-level cosmology tasks autonomously
Innovation

Methods, ideas, or system contributions that make the work stand out.

Multi-agent LLM system for scientific automation
Planning & Control strategy orchestrates workflow
Local code execution for task specialization
L
Licong Xu
Institute of Astronomy, University of Cambridge, Cambridge, United Kingdom
M
Milind Sarkar
Kavli Institute for Cosmology, University of Cambridge, Cambridge, United Kingdom
A
Anto I. Lonappan
Department of Physical Sciences, Indian Institute of Science Education and Research (IISER), Mohali, Punjab, India
Í
Íñigo Zubeldia
Institute of Astronomy, University of Cambridge, Cambridge, United Kingdom
P
Pablo Villanueva-Domingo
Computer Vision Center, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain
S
Santiago Casas
Institute for Theoretical Particle Physics and Cosmology (TTK), RWTH Aachen University, Aachen, Germany
C
Christian Fidler
Institute for Theoretical Particle Physics and Cosmology (TTK), RWTH Aachen University, Aachen, Germany
C
Chetana Amancharla
Infosys Ltd
U
Ujjwal Tiwari
Infosys Ltd
A
Adrian Bayer
Center for Computational Astrophysics, Flatiron Institute, New York, NY, USA
C
Chadi Ait Ekioui
Télécom SudParis - 9 rue Charles Fourier - 91011 Évry cedex - France
Miles Cranmer
Miles Cranmer
University of Cambridge
Machine LearningAstrophysicsFluid Dynamics
A
Adrian Dimitrov
Department of Physics, University of Cambridge, Cambridge, United Kingdom
J
James Fergusson
Department of Applied Mathematics and Theoretical Physics (DAMTP), University of Cambridge, Cambridge, United Kingdom
K
Kahaan Gandhi
Haverford College, Haverford, PA, USA
S
Sven Krippendorf
Department of Applied Mathematics and Theoretical Physics (DAMTP), University of Cambridge, Cambridge, United Kingdom
A
Andrew Laverick
Department of Physics, University of Cambridge, Cambridge, United Kingdom
Julien Lesgourgues
Julien Lesgourgues
Professor, RWTH Aachen University
Cosmology
A
Antony Lewis
Department of Physics & Astronomy, University of Sussex, Brighton BN1 9QH, UK
Thomas Meier
Thomas Meier
Chair in Structural Biology, Imperial College London
Structural biologymembrane protein biochemistry
B
Blake Sherwin
Kavli Institute for Cosmology, University of Cambridge, Cambridge, United Kingdom
K
Kristen Surrao
Department of Physics, Columbia University, New York, NY, USA
F
Francisco Villaescusa-Navarro
Center for Computational Astrophysics, Flatiron Institute, New York, NY, USA
C
Chi Wang
Google DeepMind
X
Xueqing Xu
Department of Physics, University of Cambridge, Cambridge, United Kingdom