On the handling of method failure in comparison studies

📅 2024-08-21
📈 Citations: 1
Influential: 1
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🤖 AI Summary
In methodological comparative studies, algorithmic failures—such as non-convergence or absence of output—preclude performance evaluation, yet existing literature lacks standardized guidelines for handling such failures, often overlooking or misapplying failure mitigation strategies. Method: We systematically analyze failure causes and risks of improper handling, critically examine prevalent censoring and imputation strategies for their statistical biases, and propose the principle of “context-adapted failure fallback,” establishing a framework grounded in empirically feasible fallback mechanisms. Through statistical modeling, failure root-cause diagnosis, and cross-domain empirical analysis, we identify widespread deficiencies in published studies’ failure handling practices. Contribution/Results: Two representative case studies demonstrate that inappropriate failure handling significantly distorts method rankings and undermines conclusion validity. Our work bridges critical theoretical and practical gaps in the principled treatment of algorithmic failures in empirical methodology research.

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📝 Abstract
Comparison studies in methodological research are intended to compare methods in an evidence-based manner, offering guidance to data analysts to select a suitable method for their application. To provide trustworthy evidence, they must be carefully designed, implemented, and reported, especially given the many decisions made in planning and running. A common challenge in comparison studies is to handle the ``failure'' of one or more methods to produce a result for some (real or simulated) data sets, such that their performances cannot be measured in those instances. Despite an increasing emphasis on this topic in recent literature (focusing on non-convergence as a common manifestation), there is little guidance on proper handling and interpretation, and reporting of the chosen approach is often neglected. This paper aims to fill this gap and provides practical guidance for handling method failure in comparison studies. In particular, we show that the popular approaches of discarding data sets yielding failure (either for all or the failing methods only) and imputing are inappropriate in most cases. We also discuss how method failure in published comparison studies -- in various contexts from classical statistics and predictive modeling -- may manifest differently, but is often caused by a complex interplay of several aspects. Building on this, we provide recommendations derived from realistic considerations on suitable fallbacks when encountering method failure, hence avoiding the need for discarding data sets or imputation. Finally, we illustrate our recommendations and the dangers of inadequate handling of method failure through two illustrative comparison studies.
Problem

Research questions and friction points this paper is trying to address.

Addressing method failure handling in comparison studies
Providing guidance on proper failure interpretation and reporting
Recommending realistic fallback strategies for method failures
Innovation

Methods, ideas, or system contributions that make the work stand out.

Proposes fallback strategies for method failure
Recommends realistic handling of failure factors
Discards inappropriate imputation and data removal
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Milena Wunsch
Institute for Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich (Germany); Munich Center for Machine Learning (MCML), Munich (Germany)
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Moritz Herrmann
Institute for Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, LMU Munich (Germany); Munich Center for Machine Learning (MCML), Munich (Germany)
E
Elisa Noltenius
Department of Statistics, LMU Munich, Munich (Germany)
M
Mattia Mohr
Department of Statistics, LMU Munich, Munich (Germany)
T
Tim P. Morris
MRC Clinical Trials Unit, UCL, London (UK)
Anne-Laure Boulesteix
Anne-Laure Boulesteix
Ludwig-Maximilians-Universität München
biostatisticscomputational statisticsmetascience