A Paired Point-of-Care Ultrasound Dataset for Image Quality Enhancement and Benchmarking via a cGAN Baseline

📅 2026-05-08
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🤖 AI Summary
This study addresses the challenge of poor image quality in low-performance point-of-care ultrasound (POCUS) devices, which hinders diagnostic utility in resource-limited settings. To overcome this limitation, the authors construct the first publicly available, precisely paired dataset of POCUS and high-end ultrasound images and propose a conditional generative adversarial network (cGAN) based on the pix2pix framework. Their approach integrates a U-Net generator, a hybrid loss combining L1 and SSIM metrics, and a simulation-based pretraining strategy to substantially enhance image fidelity. Experimental results demonstrate significant improvements: the structural similarity index (SSIM) increases from 0.29 to 0.54, peak signal-to-noise ratio (PSNR) rises from 19.16 dB to 22.41 dB, and no-reference quality metrics NIQE and PIQE decrease to 4.44 and 19.99, respectively, confirming the potential of deep learning to transcend inherent hardware constraints of POCUS systems.
📝 Abstract
Purpose: We aim to enhance the image quality of point-of-care ultrasound (POCUS) devices using deep learning and a novel paired dataset of POCUS and high-end ultrasound images. Approach: We collected the first accurately paired dataset using a custom-built automated gantry system of low-end POCUS and high-end ultrasound images. A conditional generative adversarial network (cGAN) was utilized based on the pix2pix architecture, with a U-Net generator that incorporates both L1 and structural similarity index (SSIM) losses to improve perceptual quality. Pretraining on a simulation dataset further boosts performance. Evaluation was performed on 1064 paired ex vivo tissue and phantom ultrasound image sets. Results: Our approach improves the SSIM from 0.29 to 0.54 and PSNR from 19.16 dB to 22.41 dB. No-reference metrics also indicate substantial enhancement, with the Natural Image Quality Evaluator (NIQE) and Perception-based Image Quality Evaluator (PIQE) scores dropping from 7.95 to 4.44 and 31.12 to 19.99, respectively. Conclusions: This work presents the first publicly available accurately paired dataset of low-end POCUS to high end ultrasound images. Additionally, our results demonstrate the potential of the proposed framework to overcome hardware limitations of handheld POCUS, enhancing its diagnostic value in low-resource and point-of-care settings. The POCUS-IQ Dataset is publicly available at https://github.com/NKI-MedTech-AI/POCUS-IQ.
Problem

Research questions and friction points this paper is trying to address.

point-of-care ultrasound
image quality enhancement
paired dataset
ultrasound imaging
diagnostic value
Innovation

Methods, ideas, or system contributions that make the work stand out.

paired ultrasound dataset
cGAN
image quality enhancement
POCUS
U-Net
L
Lennard M. van Karnenbeek
Department of Nanobiophysics, Faculty of Science and Technology, University of Twente, Drienerlolaan 5, 7522 NB Enschede, The Netherlands; Image-Guided Surgery, Department of Surgery, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
H
Hilde G. A. van der Pol
Image-Guided Surgery, Department of Surgery, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
M
Mark Wijkhuizen
Image-Guided Surgery, Department of Surgery, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
E
Eva Poelman
Department of Radiology, Netherlands Cancer Institute, Amsterdam, The Netherlands; Center for Early Cancer Detection, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
C
Caroline A. Drukker
Image-Guided Surgery, Department of Surgery, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands; Center for Early Cancer Detection, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
T
Theo Ruers
Department of Nanobiophysics, Faculty of Science and Technology, University of Twente, Drienerlolaan 5, 7522 NB Enschede, The Netherlands; Image-Guided Surgery, Department of Surgery, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands; Center for Early Cancer Detection, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
F
Freija Geldof
Image-Guided Surgery, Department of Surgery, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
Behdad Dashtbozorg
Behdad Dashtbozorg
Netherlands Cancer Institute
Medical image analysisMachine learning and Computer visionMedical ImagingSpectral tissue sensingHyperspectral imaging