Uni-Flow: a unified autoregressive-diffusion model for complex multiscale flows

📅 2026-02-17
📈 Citations: 0
Influential: 0
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🤖 AI Summary
Existing methods struggle to simultaneously capture the long-term temporal evolution and fine-scale spatial structures of complex multiscale flows, particularly in chaotic, turbulent, and physiological flow regimes. This work proposes Uni-Flow, a novel framework that unifies autoregressive and diffusion mechanisms for the first time: an autoregressive module learns low-dimensional latent variables to ensure stable long-term dynamics, while a diffusion module efficiently reconstructs high-resolution physical fields. By integrating physics-informed machine learning with high-fidelity lattice Boltzmann data, Uni-Flow achieves high-accuracy, sub-second inference in simulations of Kolmogorov flow, three-dimensional turbulence, and coarctation of the aorta—accelerating traditionally hour-long high-fidelity hemodynamic simulations to real-time performance.

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📝 Abstract
Spatiotemporal flows govern diverse phenomena across physics, biology, and engineering, yet modelling their multiscale dynamics remains a central challenge. Despite major advances in physics-informed machine learning, existing approaches struggle to simultaneously maintain long-term temporal evolution and resolve fine-scale structure across chaotic, turbulent, and physiological regimes. Here, we introduce Uni-Flow, a unified autoregressive-diffusion framework that explicitly separates temporal evolution from spatial refinement for modelling complex dynamical systems. The autoregressive component learns low-resolution latent dynamics that preserve large-scale structure and ensure stable long-horizon rollouts, while the diffusion component reconstructs high-resolution physical fields, recovering fine-scale features in a small number of denoising steps. We validate Uni-Flow across canonical benchmarks, including two-dimensional Kolmogorov flow, three-dimensional turbulent channel inflow generation with a quantum-informed autoregressive prior, and patient-specific simulations of aortic coarctation derived from high-fidelity lattice Boltzmann hemodynamic solvers. In the cardiovascular setting, Uni-Flow enables task-level faster than real-time inference of pulsatile hemodynamics, reconstructing high-resolution pressure fields over physiologically relevant time horizons in seconds rather than hours. By transforming high-fidelity hemodynamic simulation from an offline, HPC-bound process into a deployable surrogate, Uni-Flow establishes a pathway to faster-than-real-time modelling of complex multiscale flows, with broad implications for scientific machine learning in flow physics.
Problem

Research questions and friction points this paper is trying to address.

multiscale flows
long-term temporal evolution
fine-scale structure
complex dynamical systems
spatiotemporal modeling
Innovation

Methods, ideas, or system contributions that make the work stand out.

unified autoregressive-diffusion
multiscale flow modeling
temporal-spatial decoupling
fast surrogate modeling
high-fidelity hemodynamics
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