Radiuma: A Unified Zero-Code Executable Graphical Workflow Generator for Reproducible and Shareable Medical Image Analysis and Machine Learning

2026-05-22

AI Summary

This work addresses the lack of standardized, user-friendly, and reproducible software environments in medical image analysis, which hinders the widespread adoption of advanced methodologies. To overcome this limitation, the authors propose a modular, zero-code platform that enables seamless integration of image reading, visualization, registration, segmentation, radiomics feature extraction, and machine learning through intuitive graphical workflows. The platform allows users to construct, execute, and share end-to-end analysis pipelines without programming expertise. It introduces a unified, executable, and shareable cross-modality workflow system that ensures full transparency and facilitates collaborative reuse across disciplines. Supporting classification, regression, and clustering tasks, the platform significantly enhances analytical consistency, reproducibility, and interdisciplinary collaboration in clinical and translational research, as demonstrated by experimental validation.

Abstract

Medical image computing software is essential for identifying imaging biomarkers that can support diagnosis, prognosis, treatment planning, and clinical research. However, the lack of standardized, user-friendly, and reproducible software environments has limited the broader adoption of advanced medical image analysis workflows. We present Radiuma, a freely available modular platform designed to support reliable and reproducible medical image analysis across multiple modalities and file formats. Radiuma integrates image reading, visualization, registration, fusion, processing, segmentation, radiomics feature extraction, and machine learning modules for classification, regression, and clustering. Its modular design allows users to execute each component independently or connect modules through a visual workflow system, where the output of one step can be graphically passed to the next. This enables the creation of custom, executable, and reproducible multi-step pipelines without requiring extensive programming expertise. Results from each module can be inspected directly in the visualization window, providing immediate feedback on processing quality and workflow accuracy. Radiuma also supports saving and sharing customized workflows, promoting transparency, reusability, and consistency across collaborative studies. By combining flexibility, usability, and standardized analysis tools, Radiuma provides a practical environment for radiomics and machine learning research in clinical and translational settings. The platform is designed to be accessible to users with diverse expertise, including radiologists, physicists, clinicians, and data scientists.

Problem

• medical image analysis
• reproducibility
• workflow standardization
• user-friendly software
• radiomics

Innovation

• zero-code workflow
• medical image analysis
• radiomics
• reproducible research
• visual programming