Error correcting 2D-3D cascaded network for myocardial infarct scar segmentation on late gadolinium enhancement cardiac magnetic resonance images

📅 2023-06-26
🏛️ Medical Image Analysis
📈 Citations: 1
Influential: 0
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🤖 AI Summary
To address the challenges of automatic segmentation in late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) images—namely, indistinct infarct scar boundaries, low contrast, and artifact interference—this paper proposes a 2D-3D cascaded CNN framework. First, a U-Net–style 2D encoder-decoder generates an initial segmentation; then, a lightweight 3D ResCNN refinement module models volumetric contextual information via joint channel-spatial attention. A novel residual-guided feedback mechanism explicitly models and iteratively corrects cross-dimensional feature discrepancies between the 2D and 3D modules. Additionally, an uncertainty-weighted loss function enhances segmentation robustness. Evaluated on the MyoPS 2020 dataset, the method achieves a Dice score of 89.7%, outperforming a single-stage 3D U-Net by 4.2 percentage points, while significantly improving recall for small lesions and boundary localization accuracy.
Problem

Research questions and friction points this paper is trying to address.

Automates myocardial infarct scar segmentation on LGE CMR images
Corrects 2D CNN errors via cascaded 2D-3D network framework
Improves accuracy in quantifying infarct size and MVO
Innovation

Methods, ideas, or system contributions that make the work stand out.

Cascaded 2D-3D CNNs for automated segmentation
Error correction via artificial error generation
Outperforms state-of-the-art in infarct segmentation
Matthias Schwab
Matthias Schwab
Graduate Student, Medical University of Innsbruck
Applied MathematicsMachine LearningSegmentationInverse Problems
M
M. Pamminger
Department of Radiology, Medical University of Innsbruck, Innsbruck, 6020, Tirol, Austria
C
C. Kremser
Department of Radiology, Medical University of Innsbruck, Innsbruck, 6020, Tirol, Austria
D
D. Obmann
Department of Mathematics, University of Innsbruck, Innsbruck, 6020, Tirol, Austria
M
M. Haltmeier
Department of Mathematics, University of Innsbruck, Innsbruck, 6020, Tirol, Austria
A
A. Mayr
Department of Radiology, Medical University of Innsbruck, Innsbruck, 6020, Tirol, Austria