Psychosis involves a deficit of information compression in connected speech

📅 2026-09-14
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🤖 AI Summary
研究使用大型语言模型分析精神分裂症患者语言中的信息压缩缺陷,通过衡量 surprisal 差异和内在维度来揭示其与语法组织的关系。
📝 Abstract
Large language models (LLMs) with human-like performance on linguistic tasks have transformed the study of language in neurodiverse conditions. LLMs provide representations of linguistic input in the form of high-dimensional vectors (embeddings), and next-token predictions computed from these embeddings. Previous crosslinguistic evidence suggests a complexity reduction in the form of both lower intrinsic dimensionality (ID) of LLM representations and higher mean surprisal (prediction error) in psychosis. We hypothesized that these metrics reflect a general deficit of information compression in psychosis, linked to grammatical organization as what enables predictions in language.We operationalized surprisal difference as the difference between surprisal as estimated from word frequency and surprisal as based on a contextual LM, which is sensitive to grammatical organization over and above lexical concepts. Using a dataset of 144 Turkish speakers, including 106 patients with schizophrenia-spectrum disorders (SSD) - 56 with chronic schizophrenia (SZH), 33 with first-episode psychosis (FEP), and 17 with schizoaffective disorder (SZA) - and 38 healthy controls. We report: (1) Surprisal difference is attenuated in all clinical groups relative to controls, independently of word count; (2) Compressibility (intrinsic dimension) is reduced in SZH and FEP; (3) Syntactic complexity and compressibility both predict surprisal difference. These results, further refining an alteration in the geometry of the semantic space in psychosis as previously attested, suggest a broader deficit in information compression in this disorder, with a mechanistic underpinning in the operations of grammar.
Problem

Research questions and friction points this paper is trying to address.

psychosis
information compression
grammatical organization
surprisal difference
semantic space
Innovation

Methods, ideas, or system contributions that make the work stand out.

information compression
surprisal difference
intrinsic dimensionality
grammatical organization
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Claudio Palominos
Grammar and Cognition Lab, Department of Translation & Language Sciences, Universitat Pompeu Fabra, Barcelona, Spain
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Rui He
Grammar and Cognition Lab, Department of Translation & Language Sciences, Universitat Pompeu Fabra, Barcelona, Spain
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Emre Bora
Department of Neurosciences, Health Sciences Institute, Dokuz Eylul University, Izmir, Turkey
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Burcu Verim
Department of Neurosciences, Health Sciences Institute, Dokuz Eylul University, Izmir, Turkey
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Cemal Demirlek
Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Massachusetts, United States of America
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Berna Yalincetin
Department of Neurosciences, Health Sciences Institute, Dokuz Eylul University, Izmir, Turkey
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Philipp Homan
Department of Adult Psychiatry and Psychotherapy, University of Zurich, Zurich, Switzerland; Neuroscience Center Zurich, University of Zurich and ETH Zurich, Zurich, Switzerland
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Wolfram Hinzen
Grammar and Cognition Lab, Department of Translation & Language Sciences, Universitat Pompeu Fabra, Barcelona, Spain; Institut Català de Recerca i Estudis Avançats (ICREA), Barcelona, Spain