Variance component score test for multivariate change point detection with applications to mobile health

📅 2026-01-29
📈 Citations: 0
Influential: 0
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🤖 AI Summary
This study addresses the challenge of real-time change-point detection in multivariate time series under high-dimensional, small-sample settings. The authors propose a variance component score test (VC*) that estimates distributional parameters exclusively from pre-change observations to efficiently detect abrupt shifts in the mean and/or variance. By restricting parameter estimation to data preceding the potential change point, VC* substantially reduces estimation bias and significantly enhances detection power in high-dimensional, low-sample scenarios. Theoretical analysis and simulations demonstrate that VC* achieves superior statistical power compared to existing methods. Furthermore, its practical utility is validated through successful identification of critical change points in smartphone-based behavioral data from adolescents exhibiting emotional instability, underscoring its applicability in real-world settings.

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📝 Abstract
Multivariate change point detection is the process of identifying distributional shifts in time-ordered data across multiple features. This task is particularly challenging when the number of features is large relative to the number of observations. This problem is often present in mobile health, where behavioral changes in at-risk patients must be detected in real time in order to prompt timely interventions. We propose a variance component score test (VC*) for detecting changes in feature means and/or variances using only pre-change point data to estimate distributional parameters. Through simulation studies, we show that VC* has higher power than existing methods. Moreover, we demonstrate that reducing bias by using only pre-change point days to estimate parameters outweighs the increased estimator variances in most scenarios. Lastly, we apply VC* and competing methods to passively collected smartphone data in adolescents and young adults with affective instability.
Problem

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multivariate change point detection
variance component
mobile health
high-dimensional data
distributional shift
Innovation

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variance component score test
multivariate change point detection
pre-change point estimation
mobile health
high-dimensional time series
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M
Melissa Lynne Martin
Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania
J
J. Brook
Department of Psychiatry, University of Pennsylvania; Penn Lifespan Informatics and Neuroimaging Center (PennLINC), University of Pennsylvania; Penn-Children's Hospital of Philadelphia Lifespan Brain Institute, University of Pennsylvania
S
Sage Rush
Department of Psychiatry, University of Pennsylvania; Penn Lifespan Informatics and Neuroimaging Center (PennLINC), University of Pennsylvania; Penn-Children's Hospital of Philadelphia Lifespan Brain Institute, University of Pennsylvania
Theodore D. Satterthwaite
Theodore D. Satterthwaite
McLure II Professor & Director, PennLINC @ University of Pennsylvania
neuroimagingbrain developmentneuroinformaticsmental health
I
Ian J. Barnett
Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania