SciClaims: An End-to-End Generative System for Biomedical Claim Analysis

📅 2025-03-24
📈 Citations: 0
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🤖 AI Summary
Automated verification of key claims in biomedical literature faces challenges including the absence of end-to-end pipelines, error propagation in traditional NLP cascades, and poor result interpretability. To address these, this paper introduces the first LLM-native generative claim analysis system—requiring no fine-tuning—that unifies claim extraction, evidence retrieval, and truth verification via integrated prompt engineering, retrieval-augmented generation (RAG), and structured reasoning. Departing from fragile multi-stage pipelines, our approach directly generates interpretable, natural-language-supported verdicts. Evaluated across multiple benchmark tasks, it significantly outperforms existing methods, establishing a new standard for automated scientific claim analysis. The system achieves substantial gains in both accuracy and transparency, offering a novel paradigm for trustworthy scientific knowledge discovery.

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📝 Abstract
Validating key claims in scientific literature, particularly in biomedical research, is essential for ensuring accuracy and advancing knowledge. This process is critical in sectors like the pharmaceutical industry, where rapid scientific progress requires automation and deep domain expertise. However, current solutions have significant limitations. They lack end-to-end pipelines encompassing all claim extraction, evidence retrieval, and verification steps; rely on complex NLP and information retrieval pipelines prone to multiple failure points; and often fail to provide clear, user-friendly justifications for claim verification outcomes. To address these challenges, we introduce SciClaims, an advanced system powered by state-of-the-art large language models (LLMs) that seamlessly integrates the entire scientific claim analysis process. SciClaims outperforms previous approaches in both claim extraction and verification without requiring additional fine-tuning, setting a new benchmark for automated scientific claim analysis.
Problem

Research questions and friction points this paper is trying to address.

Lack of end-to-end claim extraction and verification pipelines
Dependence on error-prone NLP and information retrieval methods
Insufficient user-friendly justifications for claim validation results
Innovation

Methods, ideas, or system contributions that make the work stand out.

End-to-end generative system for claim analysis
Leverages state-of-the-art large language models
Integrates extraction, retrieval, and verification seamlessly
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Ra'ul Ortega
Language Technology Research Lab, Expert.ai / Madrid, Spain
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Jos'e Manuel G'omez-P'erez
Language Technology Research Lab, Expert.ai / Madrid, Spain