Epidemic Informatics and Control: A Holistic Approach from System Informatics to Epidemic Response and Risk Management in Public Health

📅 2026-07-15
📈 Citations: 0
Influential: 0
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🤖 AI Summary
This study addresses the systemic gaps in public health emergency response revealed by the COVID-19 pandemic, particularly the absence of a comprehensive, data-driven risk management framework. To bridge this gap, the work proposes the first adaptation of the industrial DMAIC (Define, Measure, Analyze, Improve, Control) systems informatics paradigm to epidemic control. By integrating medical diagnostics, statistical sampling, data visualization, artificial intelligence, telemedicine, and resource optimization, the framework establishes an intelligent decision-support system spanning the entire epidemic lifecycle. This approach not only enhances the resilience and responsiveness of health systems but also fosters interdisciplinary convergence between systems informatics and public health, offering a replicable and scalable methodological foundation for managing future public health emergencies.
📝 Abstract
This paper presents a holistic systems informatics approach, i.e., Define, Measure, Analyze, Improve, and Control (DMAIC), for epidemic response and management through the intensive use of data, statistics and optimization. Despite the sustained successes of system informatics in a variety of established industries such as manufacturing, logistics, services and beyond, there is a dearth of concentrated review and application of the data-driven DMAIC approach in the context of epidemic outbreaks. First, we define specific challenges posed by epidemic outbreaks to populational health, health systems, as well as economic challenges to different industries such as retailing, education and manufacturing. Second, we present a review of medical testing and statistical sampling methods for data collection, as well as existing efforts in data management and data visualization. Third, we discuss the importance to realizing the full potential of data for epidemic insights, and emphasize the need to leverage analytical methods and tools for decision support. Fourth, an epidemic brings imperative changes to health systems. We discuss the new trend of healthcare solutions to improve system resilience, including telehealth, artificial intelligence, resource allocation, and system re-design. In closing, prescriptive approaches are discussed to optimize the health policies and action strategies for controlling the spread of virus. We posit that this work will catalyze more in-depth investigations and multi-disciplinary research efforts to accelerate the application of system informatics methods and tools in epidemic response and risk management.
Problem

Research questions and friction points this paper is trying to address.

Epidemic Informatics
Public Health
DMAIC
Epidemic Response
Risk Management
Innovation

Methods, ideas, or system contributions that make the work stand out.

DMAIC
systems informatics
epidemic response
data-driven decision making
health system resilience
Hui Yang
Hui Yang
Gary and Sheila Bello Chair Professor, IISE Fellow, Pennsylvania State University
Industrial and Systems EngineeringHealthcare Systems EngineeringEngineering statistics
Siqi Zhang
Siqi Zhang
Assistant Professor, Nanjing University
OptimizationNonconvex OptimizationMachine Learning
R
Runsang Liu
Center for Health Organization Transformation, The Pennsylvania State University, University Park, PA, USA
A
Alexander Krall
Center for Health Organization Transformation, The Pennsylvania State University, University Park, PA, USA
Y
Yidan Wang
Center for Health Organization Transformation, The Pennsylvania State University, University Park, PA, USA
M
Marta Ventura
Center for Health Organization Transformation, The Pennsylvania State University, University Park, PA, USA
C
Chris Deflitch
Department of Emergency Medicine, Vice president, Penn State Health, Chief medical information officer, Milton S. Hershey Medical Center