Networked Intelligence: Active Shared Context Graphs for Human-AI Team Science

📅 2026-07-14
📈 Citations: 0
Influential: 0
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🤖 AI Summary
This work addresses the challenge of inefficient collaboration between multi-role human experts and AI systems in complex scientific research by introducing a novel paradigm termed “networked intelligence.” It frames scientific collaboration as a sparse conditional computation problem, explicitly distinguishing tasks solvable by individual agents from those requiring irreducible, shared contextual understanding. To operationalize this paradigm, we present Mycelium—an active shared workspace that automatically captures and interconnects hypotheses and observations generated by both humans and AI through proactive context graph construction, a multi-user collaborative reasoning architecture, and dynamic knowledge routing. Evaluated in multi-omics biological experiments, the system demonstrates its ability to transform localized analyses into cross-domain mechanistic constraints via contextual routing and effectively guide the design of novel experiments.
📝 Abstract
Most AI-for-science systems focus on scaling a single reasoning process through better models, larger context windows, long-horizon agentic execution, or digital co-scientists working with one principal user. However, challenging scientific problems are rarely solved by one reasoner alone. They are solved by teams whose members bring different priors, experimental backgrounds, tacit knowledge, and domain-trained intuitions. The open problem is therefore not only how to scale models, but how to cultivate networked intelligence: scaling the connections between humans and AI systems so that a result or hypothesis produced in one context reaches another person, agent, instrument, or robot that can act on it. We introduce Mycelium, an active shared workspace that automatically connects researchers and AI agents as a multi-user co-scientist. As human users and agents work, the system captures important observations and hypotheses, tracks how they relate to the team's evolving model, and routes them to the person or agent whose next decision they can inform. We evaluate Mycelium in its first empirical test, a biological multi-omics campaign in which routed shared context turned a local analytical finding into a cross-expert mechanistic constraint and ultimately into an experimental design. We also give networked intelligence a computational account as sparse conditional computation over distributed scientific contexts. This account distinguishes when a scaled standalone agent can match the network from when independent expertise and non-mergeable contexts make the network irreducible.
Problem

Research questions and friction points this paper is trying to address.

networked intelligence
human-AI collaboration
shared context
team science
scientific reasoning
Innovation

Methods, ideas, or system contributions that make the work stand out.

networked intelligence
active shared context graphs
multi-user co-scientist
sparse conditional computation
human-AI team science
Sutanay Choudhury
Sutanay Choudhury
Pacific Northwest National Laboratory
Artificial Intelligence
J
Jeffrey J. Czajka
Pacific Northwest National Laboratory
L
Lummy M. O. Monteiro
Pacific Northwest National Laboratory
E
Erin Bredeweg
Pacific Northwest National Laboratory
Jason McDermott
Jason McDermott
Scientist Pacific Northwest National Laboratory
machine learninginfectious diseasestroke modelingbiological networkstopology
K
Katherine Wolf
Pacific Northwest National Laboratory
A
Alex Beliaev
Pacific Northwest National Laboratory
J
Josh Elmore
Pacific Northwest National Laboratory
P
Paul Piehowski
Pacific Northwest National Laboratory
K
Kylee Tate
Pacific Northwest National Laboratory
Y
Yuqian Gao
Pacific Northwest National Laboratory
A
Aivett Bilbao
Pacific Northwest National Laboratory
K
Kelly Stratton
Pacific Northwest National Laboratory
Scott Baker
Scott Baker
Pacific Northwest National Laboratory
biotechnologymycologygeneticscell biologygenomics
J
Jaydeep P. Bardhan
Pacific Northwest National Laboratory
K
Kristin Burnum Johnson
Pacific Northwest National Laboratory
Chris Oehmen
Chris Oehmen
Pacific Northwest National Laboratory
computational biologycybersecruity
Robert Rallo
Robert Rallo
Pacific Northwest National Laboratory
data sciencesmachine learningurban data sciencecomputational toxicologybioinformatics