SKG-LLM: Developing a Mathematical Model for Stroke Knowledge Graph Construction Using Large Language Models

📅 2025-03-09
📈 Citations: 0
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🤖 AI Summary
Existing stroke-domain knowledge graphs (KGs) suffer from insufficient accuracy and semantic depth. Method: This paper proposes a novel KG construction framework integrating large language models (LLMs) with mathematical modeling. GPT-4 is systematically embedded across all KG construction stages—literature preprocessing, entity-relation extraction, and embedding generation—complemented by expert validation to ensure quality. A mathematical optimization model refines graph topology and enforces semantic consistency. Contribution/Results: The approach achieves state-of-the-art performance with precision (0.923) and recall (0.918), outperforming Wikidata and WN18RR benchmarks. The resulting high-quality stroke-domain KG comprises 2,692 nodes (13 types) and 5,012 edges (24 types). In the fully automated construction phase, it attains precision of 0.906 and recall of 0.923.

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📝 Abstract
The purpose of this study is to introduce SKG-LLM. A knowledge graph (KG) is constructed from stroke-related articles using mathematical and large language models (LLMs). SKG-LLM extracts and organizes complex relationships from the biomedical literature, using it to increase the accuracy and depth of KG in stroke research. In the proposed method, GPT-4 was used for data pre-processing, and the extraction of embeddings was also done by GPT-4 in the whole KG construction process. The performance of the proposed model was tested with two evaluation criteria: Precision and Recall. For further validation of the proposed model, GPT-4 was used. Compared with Wikidata and WN18RR, the proposed KG-LLM approach performs better, especially in precision and recall. By including GPT-4 in the preprocessing process, the SKG-LLM model achieved a precision score of 0.906 and a recall score of 0.923. Expert reviews further improved the results and increased precision to 0.923 and recall to 0.918. The knowledge graph constructed by SKG-LLM contains 2692 nodes and 5012 edges, which are 13 distinct types of nodes and 24 types of edges.
Problem

Research questions and friction points this paper is trying to address.

Develops SKG-LLM for stroke knowledge graph construction.
Uses GPT-4 for data preprocessing and embedding extraction.
Improves precision and recall in stroke research knowledge graphs.
Innovation

Methods, ideas, or system contributions that make the work stand out.

Uses GPT-4 for data preprocessing and embeddings
Constructs stroke knowledge graph with high precision
Integrates expert reviews to enhance model accuracy
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