X$^{2}$-Gaussian: 4D Radiative Gaussian Splatting for Continuous-time Tomographic Reconstruction

📅 2025-03-27
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🤖 AI Summary
Existing 4D-CT reconstruction relies on discrete respiratory phase binning, causing motion misalignment and requiring specialized gating hardware. To address this, we propose a hardware-free, continuous-time 4D-CT reconstruction framework. Our method introduces dynamic radial Gaussian splatting into tomographic reconstruction—enabling differentiable, spatiotemporally continuous deformation modeling of anatomical structures. We further design a physiology-driven projection-domain periodic consistency loss to enable self-supervised learning of patient-specific respiratory dynamics. A spatiotemporal encoder-decoder network jointly optimizes the reconstructed image sequence and the underlying motion field. Experiments demonstrate a 9.93 dB PSNR improvement over conventional binning-based methods and a 2.25 dB gain over prior Gaussian splatting approaches. The framework significantly enhances motion fidelity and clinical practicality while eliminating hardware dependencies.

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📝 Abstract
Four-dimensional computed tomography (4D CT) reconstruction is crucial for capturing dynamic anatomical changes but faces inherent limitations from conventional phase-binning workflows. Current methods discretize temporal resolution into fixed phases with respiratory gating devices, introducing motion misalignment and restricting clinical practicality. In this paper, We propose X$^2$-Gaussian, a novel framework that enables continuous-time 4D-CT reconstruction by integrating dynamic radiative Gaussian splatting with self-supervised respiratory motion learning. Our approach models anatomical dynamics through a spatiotemporal encoder-decoder architecture that predicts time-varying Gaussian deformations, eliminating phase discretization. To remove dependency on external gating devices, we introduce a physiology-driven periodic consistency loss that learns patient-specific breathing cycles directly from projections via differentiable optimization. Extensive experiments demonstrate state-of-the-art performance, achieving a 9.93 dB PSNR gain over traditional methods and 2.25 dB improvement against prior Gaussian splatting techniques. By unifying continuous motion modeling with hardware-free period learning, X$^2$-Gaussian advances high-fidelity 4D CT reconstruction for dynamic clinical imaging. Project website at: https://x2-gaussian.github.io/.
Problem

Research questions and friction points this paper is trying to address.

Enables continuous-time 4D-CT reconstruction without phase discretization
Eliminates dependency on external respiratory gating devices
Improves reconstruction accuracy over traditional and prior methods
Innovation

Methods, ideas, or system contributions that make the work stand out.

Dynamic radiative Gaussian splatting for 4D-CT
Self-supervised respiratory motion learning
Physiology-driven periodic consistency loss
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