A multicenter benchmark and clinically structured metric for coronary CTA report generation

2026-09-01

AI Summary

研究建立了多中心基准和临床结构化指标CSM_CCTA，用于评估冠状动脉CTA报告自动生成的准确性与解剖特异性。

Abstract

Reliable evaluation of automated coronary computed tomography angiography (CCTA) report generation requires standardized multicentre benchmarks and clinically structured metrics. We established a four-centre benchmark comprising 3,021 CCTA series from 818 patient-report pairs to evaluate seven open-source three-dimensional vision-language models. We developed CSM$_{\text{CCTA}}$, a clinically structured metric for CCTA report evaluation, with patient-, vessel-, and segment-level variables defined according to clinical guidelines. Report pairs are compared at the finest shared anatomical level, and the contributions of different clinical components are weighted based on expert assessments. We estimated these weights using 70 expert-scored cases and evaluated clinical alignment in a non-overlapping set of 30 cases. CSM$_{\text{CCTA}}$ showed a strong correlation with radiologist scores (Pearson's $r=0.97$, $p<0.001$), exceeding the next-best metric, FORTE ($r=0.70$), by 0.27, and agreed with expert preferences in 115 of 160 pairwise comparisons (71.9\%). Under controlled perturbations, CSM$_{\text{CCTA}}$ remained stable to clinically equivalent wording and decreased monotonically with progressive information omission. In the multicenter benchmark, the CCTA-trained C2RG model achieved the highest CSM$_{\text{CCTA}}$ scores across all four hospitals, although its performance remained far from optimal. In contrast, CCTA-irrelevant reports accounted for up to 98.7\% of the outputs from generalist models. Together, the benchmark provides a standardized setting for model comparison, while CSM$_{\text{CCTA}}$ enables clinically structured evaluation of finding agreement and anatomical specificity. These results support a more clinically aligned and anatomically resolved approach to evaluating CCTA report generation. Code is available at https://openi.pcl.ac.cn/OpenMedIA/CSM_CCTA.

Problem

• CCTA
• report generation
• benchmark
• structured metric
• clinical evaluation

Innovation

• multicenter benchmark
• clinically structured metric
• CCTA report generation
• CSM_CCTA