LatentVerse: A Framework for Understanding Shared and Modality-Specific Information in Multimodal Latent Representations

📅 2026-09-10
📈 Citations: 0
Influential: 0
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🤖 AI Summary
本文提出了LatentVerse框架,通过分解多模态潜在表示为共享和特定模态成分来解决现有分析工作流程中缺乏统一及多模态分析的问题。
📝 Abstract
Latent embeddings have become a central data abstraction in modern machine learning, especially in biomedicine, where foundation models are increasingly used to encode multimodal data like clinical text, medical images, omics, and physiological signals. However, the utility and value of these representations depends on understanding their quality, structure, and the information they encode. Existing analysis workflows for evaluating representations remain fragmented across custom scripts, isolated metrics, and most importantly lack multimodal analysis, limiting accessibility and reproducibility. We present LatentVerse, a representation analysis resource that combines a web-based visual analytics platform for accessible, report-driven exploration with a command-line interface for scalable technical workflows. LatentVerse unifies diagnostics for various representation quality metrics and extends to multimodal settings by decomposing embeddings into shared and modality-specific components. We evaluate LatentVerse through controlled unimodal and multimodal simulations, discovery-oriented analyses on real biomedical embeddings, and a user study across diverse use cases. By supporting thorough and interpretable evaluation of latent spaces, LatentVerse makes foundation model representations more understandable in biomedical and data science applications.
Problem

Research questions and friction points this paper is trying to address.

latent representations
multimodal data
representation quality
biomedicine
reproducibility
Innovation

Methods, ideas, or system contributions that make the work stand out.

Multimodal Analysis
Latent Representations
Visualization Platform
Shared and Modality-Specific Components
M
Majd Alafrange
Machine Learning for Health (ML4H), Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
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Samuel Friedman
Machine Learning for Health (ML4H), Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
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John Kitonyo
Machine Learning for Health (ML4H), Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
S
Sana Tonekaboni
Machine Learning for Health (ML4H), Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA; Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; The Schmidt Center, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
M
Mahnaz Maddah
Machine Learning for Health (ML4H), Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA