ADELIA: Automatic Differentiation for Efficient Laplace Inference Approximations

📅 2026-05-07
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🤖 AI Summary
This work addresses the scalability limitations of traditional Integrated Nested Laplace Approximation (INLA) methods, which rely on finite-difference approximations for gradient computation—a strategy whose computational cost and energy consumption grow prohibitively with the dimensionality of hyperparameters, hindering application to large-scale spatiotemporal Bayesian inference. To overcome this bottleneck, the study introduces, for the first time, structure-aware reverse-mode automatic differentiation into the INLA framework, leveraging model sparsity to design a multi-GPU-efficient backpropagation algorithm tailored for high-dimensional sparse latent Gaussian models. Evaluated on a real-world air pollution monitoring task involving 1.9 million latent variables, the proposed approach achieves 4.2–7.9× speedup per gradient evaluation and exhibits markedly improved convergence stability. Moreover, it reduces energy consumption by 5–8× compared to an optimized finite-difference baseline.
📝 Abstract
Spatio-temporal Bayesian inference drives environmental and health sciences using latent Gaussian models. Integrated Nested Laplace Approximations (INLA) enable inference for these models at HPC scale but rely on derivative-based optimization over $d$ hyperparameters. State-of-the-art INLA implementations approximate derivatives via central finite differences (FD), requiring $2d{+}1$ evaluations. These evaluations are embarrassingly parallel, but total work and energy grow with $d$, limiting time-to-solution under fixed budgets. Reverse-mode automatic differentiation (AD) computes exact gradients independently of $d$, but its efficient application to INLA's structured-sparse kernels is an open challenge. We present ADELIA, the first AD-enabled INLA implementation with a structure-exploiting multi-GPU backward pass leveraging model sparsity. We evaluate ADELIA on ten benchmark models, including real-world air-pollution monitoring. We achieve $4.2$--$7.9\times$ per-gradient speedups and reliable convergence on production-scale models with up to 1.9M latent variables, where FD struggles. Even when scaled to 16--32 GPUs to match ADELIA's wall-clock time, FD consumes $5$--$8\times$ more energy.
Problem

Research questions and friction points this paper is trying to address.

Integrated Nested Laplace Approximations
automatic differentiation
Bayesian inference
hyperparameter optimization
computational efficiency
Innovation

Methods, ideas, or system contributions that make the work stand out.

Automatic Differentiation
INLA
Structured Sparsity
Multi-GPU
Bayesian Inference