Automatic Robotic-Assisted Diffuse Reflectance Spectroscopy Scanning System

📅 2025-03-11
📈 Citations: 0
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🤖 AI Summary
Current intraoperative tumor margin identification relies heavily on manual operation, suffering from low scanning efficiency and poor inter-observer consistency. To address this, we present the first fully automated robotic-assisted diffuse reflectance spectroscopy (DRS) scanning system. Our approach integrates vision-based servo control with an adaptive contact module, incorporating a custom height-compensation mechanism, real-time spectral acquisition, and synchronized localization for large-area, in situ, stable, and repeatable optical scanning. Compared to conventional manual point-wise measurements, our system overcomes limitations in coverage area and procedural consistency: it achieves clinical gold-standard spatial accuracy and spectral reproducibility comparable to expert manual operation, enabling autonomous, high-throughput intraoperative tissue composition assessment. This work establishes the first clinically translatable automated hardware platform for optical guidance in precision tumor resection.

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📝 Abstract
Diffuse Reflectance Spectroscopy (DRS) is a well-established optical technique for tissue composition assessment which has been clinically evaluated for tumour detection to ensure the complete removal of cancerous tissue. While point-wise assessment has many potential applications, incorporating automated large-area scanning would enable holistic tissue sampling with higher consistency. We propose a robotic system to facilitate autonomous DRS scanning with hybrid visual servoing control. A specially designed height compensation module enables precise contact condition control. The evaluation results show that the system can accurately execute the scanning command and acquire consistent DRS spectra with comparable results to the manual collection, which is the current gold standard protocol. Integrating the proposed system into surgery lays the groundwork for autonomous intra-operative DRS tissue assessment with high reliability and repeatability. This could reduce the need for manual scanning by the surgeon while ensuring complete tumor removal in clinical practice.
Problem

Research questions and friction points this paper is trying to address.

Develops robotic system for autonomous DRS scanning
Ensures precise tissue contact for accurate spectroscopy
Aims to improve tumor detection and removal reliability
Innovation

Methods, ideas, or system contributions that make the work stand out.

Robotic system for autonomous DRS scanning
Hybrid visual servoing control for precision
Height compensation module for contact control
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Kaizhong Deng
Hamlyn Centre for Robotic Surgery, Institute of Global Health Innovation, Imperial College London; Department of Surgery and Cancer, Imperial College London
C
Christopher J. Peters
Department of Surgery and Cancer, Imperial College London
G
George P. Mylonas
Hamlyn Centre for Robotic Surgery, Institute of Global Health Innovation, Imperial College London; Department of Surgery and Cancer, Imperial College London
Daniel S. Elson
Daniel S. Elson
Professor of Surgical Imaging and Biophotonics, Department of Surgery and Cancer, Imperial College
EndoscopySurgical ImagingPolarization-resolved EndoscopyMultispectral EndoscopyImage-Guided