MetaCaDI: A Meta-Learning Framework for Scalable Causal Discovery with Unknown Interventions

📅 2025-10-25
📈 Citations: 0
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🤖 AI Summary
Causal graph discovery under high data costs and unknown interventions remains challenging. Method: This paper proposes the first framework unifying causal structure learning and intervention target identification as a meta-learning task. It replaces bilevel optimization with an analytical adaptive mechanism, integrating Bayesian modeling and closed-form parameter updates to enable cross-experiment sharing of causal structure estimation and intervention localization. Contributions/Results: We establish the first meta-learning paradigm jointly addressing causal discovery and unknown intervention identification; avoid implicit gradient differentiation, thereby significantly improving training stability and few-shot generalization. On synthetic and real-world gene expression datasets, our method achieves high-accuracy causal graph recovery and intervention node identification using only 10 samples—outperforming state-of-the-art approaches substantially.

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📝 Abstract
Uncovering the underlying causal mechanisms of complex real-world systems remains a significant challenge, as these systems often entail high data collection costs and involve unknown interventions. We introduce MetaCaDI, the first framework to cast the joint discovery of a causal graph and unknown interventions as a meta-learning problem. MetaCaDI is a Bayesian framework that learns a shared causal graph structure across multiple experiments and is optimized to rapidly adapt to new, few-shot intervention target prediction tasks. A key innovation is our model's analytical adaptation, which uses a closed-form solution to bypass expensive and potentially unstable gradient-based bilevel optimization. Extensive experiments on synthetic and complex gene expression data demonstrate that MetaCaDI significantly outperforms state-of-the-art methods. It excels at both causal graph recovery and identifying intervention targets from as few as 10 data instances, proving its robustness in data-scarce scenarios.
Problem

Research questions and friction points this paper is trying to address.

Develops scalable causal discovery framework for unknown interventions
Learns shared causal graph across multiple experimental datasets
Enables few-shot intervention target prediction with limited data
Innovation

Methods, ideas, or system contributions that make the work stand out.

Meta-learning framework for causal discovery
Bayesian model with analytical adaptation
Closed-form solution bypasses gradient optimization
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