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Xuanwu Hospital

Academic institutionasia · cn
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Selected work

Representative Papers

Enriched text-guided variational multimodal knowledge distillation network (VMD) for automated diagnosis of plaque vulnerability in 3D carotid artery MRI

Sep 15, 2025

This study addresses the challenges of scarce expert annotations and modality heterogeneity in diagnosing plaque vulnerability from 3D carotid MRI. We propose a text-guided variational multimodal knowledge distillation (VMD) framework. Methodologically, it integrates a 3D CNN with a text encoder and employs variational inference to explicitly model predictive uncertainty, while leveraging domain knowledge embedded in radiology reports to enable cross-modal image–text alignment and knowledge transfer. Our key contribution lies in embedding expert priors into the variational learning paradigm, enabling robust diagnosis of unlabeled imaging data under minimal supervision. Evaluated on a proprietary clinical dataset, VMD significantly outperforms unimodal and conventional multimodal baselines: with only 5% labeled data, it achieves 92.3% diagnostic accuracy. The framework establishes a novel, interpretable, and generalizable multimodal learning paradigm for low-resource medical image analysis.

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Latest Papers

Enriched text-guided variational multimodal knowledge distillation network (VMD) for automated diagnosis of plaque vulnerability in 3D carotid artery MRI

Sep 15, 2025

This study addresses the challenges of scarce expert annotations and modality heterogeneity in diagnosing plaque vulnerability from 3D carotid MRI. We propose a text-guided variational multimodal knowledge distillation (VMD) framework. Methodologically, it integrates a 3D CNN with a text encoder and employs variational inference to explicitly model predictive uncertainty, while leveraging domain knowledge embedded in radiology reports to enable cross-modal image–text alignment and knowledge transfer. Our key contribution lies in embedding expert priors into the variational learning paradigm, enabling robust diagnosis of unlabeled imaging data under minimal supervision. Evaluated on a proprietary clinical dataset, VMD significantly outperforms unimodal and conventional multimodal baselines: with only 5% labeled data, it achieves 92.3% diagnostic accuracy. The framework establishes a novel, interpretable, and generalizable multimodal learning paradigm for low-resource medical image analysis.

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