Anatomy Guided Coronary Artery Segmentation from CCTA Using Spatial Frequency Joint Modeling
To address segmentation instability in coronary artery CT angiography—caused by fine vessel calibers, complex branching patterns, ambiguous boundaries, and myocardial interference—this paper proposes a 3D wavelet-based encoder-decoder network with joint spatial-frequency modeling. The method innovatively integrates myocardium-anatomy-guided priors, residual attention enhancement, and 3D inverse wavelet transforms to achieve structural-consistent multi-scale feature encoding and decoding. Additionally, overlapping voxel block training and multi-scale feature fusion are introduced to improve representation of small distal branches. Evaluated on the ImageCAS dataset, the model achieves a Dice coefficient of 0.8082, sensitivity of 0.7946, precision of 0.8471, and a 95th-percentile Hausdorff distance (HD95) of 9.77 mm—significantly outperforming state-of-the-art 3D segmentation methods.