Institution profile

Tinbergen Institute

Academic institutioneurope · nl
Official website
Research library4linked papers
Opportunities0open roles
Selected work

Representative Papers

Real-time Program Evaluation using Anytime-valid Rank Tests

Apr 30, 2025

This paper addresses the limitation of traditional counterfactual mean estimation methods—such as difference-in-differences and synthetic control—in program evaluation under streaming data settings, where real-time causal inference is infeasible. We propose a sequential causal inference framework valid at any time point. Our key innovation is the first integration of exchangeability assumptions with sequential rank testing, enabling an anytime-valid hypothesis test that requires no prespecified sample size and supports both early stopping and delayed rejection. Theoretically, the method strictly controls Type-I error even under mild violations of exchangeability. Simulation results show a modest reduction in asymptotic statistical power but substantial gains in decision timeliness and adaptability. This framework provides a practical, real-time causal inference tool for dynamic policy evaluation.

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Gene-environment interplay and public policies

Mar 27, 2025

Existing gene–environment interaction (GxE) research lacks a policy-oriented theoretical framework and empirically appropriate methodologies, hindering the identification of heterogeneous policy effects across genetically distinct subpopulations. Method: This project develops the first policy-goal-driven GxE taxonomy, overcoming limitations of conventional interaction-term modeling. It integrates multilevel GxE modeling, polygenic index (PGI) quantile interaction analysis, and natural experiments in education policy to systematically map empirical GxE evidence for educational interventions. Contribution/Results: The study delivers an actionable methodological framework and empirical benchmarks for designing precision, equity-centered education policies. By explicitly linking genetic susceptibility with policy-relevant environmental variation, it substantially enhances the policy relevance, interpretability, and translational value of GxE research—bridging a critical gap between behavioral genetics and evidence-based policymaking.

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Recent publications

Latest Papers

Real-time Program Evaluation using Anytime-valid Rank Tests

Apr 30, 2025

This paper addresses the limitation of traditional counterfactual mean estimation methods—such as difference-in-differences and synthetic control—in program evaluation under streaming data settings, where real-time causal inference is infeasible. We propose a sequential causal inference framework valid at any time point. Our key innovation is the first integration of exchangeability assumptions with sequential rank testing, enabling an anytime-valid hypothesis test that requires no prespecified sample size and supports both early stopping and delayed rejection. Theoretically, the method strictly controls Type-I error even under mild violations of exchangeability. Simulation results show a modest reduction in asymptotic statistical power but substantial gains in decision timeliness and adaptability. This framework provides a practical, real-time causal inference tool for dynamic policy evaluation.

0 citationsRead paper

Gene-environment interplay and public policies

Mar 27, 2025

Existing gene–environment interaction (GxE) research lacks a policy-oriented theoretical framework and empirically appropriate methodologies, hindering the identification of heterogeneous policy effects across genetically distinct subpopulations. Method: This project develops the first policy-goal-driven GxE taxonomy, overcoming limitations of conventional interaction-term modeling. It integrates multilevel GxE modeling, polygenic index (PGI) quantile interaction analysis, and natural experiments in education policy to systematically map empirical GxE evidence for educational interventions. Contribution/Results: The study delivers an actionable methodological framework and empirical benchmarks for designing precision, equity-centered education policies. By explicitly linking genetic susceptibility with policy-relevant environmental variation, it substantially enhances the policy relevance, interpretability, and translational value of GxE research—bridging a critical gap between behavioral genetics and evidence-based policymaking.

0 citationsRead paper