Unsupervised Anomaly Detection for Image Dataset Quality Assurance in Multi-Center Breast MRI
This study addresses quality control challenges in multi-center breast MRI by proposing an unsupervised anomaly detection framework. Through a controlled benchmark encompassing 17 anomaly types, we identify near out-of-distribution (OOD) detection as a critical bottleneck. To overcome this, we introduce a novel approach integrating projection methods, 3D reconstruction, and hybrid OOD detection, enhanced with domain-specific features and positional encoding for precise identification. Experiments demonstrate that the projection method achieves an AUROC of 0.954, while 3D reconstruction exhibits superior generalization, underscoring the necessity of domain adaptation. This research establishes a scalable, automated quality control paradigm, providing essential benchmarks and methodological support for data safety in medical AI, although detecting implants remains challenging.