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Tianjin University of Science and Technology

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Research library5linked papers
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Selected work

Representative Papers

IPv2: An Improved Image Purification Strategy for Real-World Ultra-Low-Dose Lung CT Denoising

Feb 22, 2026

This work addresses the limitations of existing ultra-low-dose lung CT denoising methods, which struggle to effectively suppress noise in both background regions and pulmonary parenchyma and lack a principled strategy for constructing evaluation labels. To overcome these challenges, the authors propose a novel image purification framework employing a three-stage strategy—background removal, controllable noise injection, and denoising—that enhances the model’s joint denoising capability for both regions during training and enables more realistic label construction during testing. This approach represents the first systematic refinement of the image purification pipeline, is compatible with various mainstream denoising architectures, and demonstrates significant improvements in background suppression and lung structure recovery on real patient CT scans acquired at only 2% of standard radiation dose.

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A Denoising Framework for Real-World Ultra-Low Dose Lung CT Images Based on an Image Purification Strategy

Oct 08, 2025

Ultra-low-dose CT (uLDCT) reduces radiation exposure but introduces severe noise, artifacts, and structural misalignment with normal-dose CT (NDCT), degrading the performance of existing denoising methods. To address this, we propose an image purification strategy that, for the first time, generates structurally aligned uLDCT–NDCT paired samples from real clinical data. Building upon this, we design a Frequency-domain Flow Matching (FFM) model that explicitly models the noise distribution in the frequency domain while enforcing anatomical structure consistency via frequency-aware constraints. The resulting dataset and FFM framework significantly improve the denoising performance of multiple state-of-the-art models on real-world uLDCT scans, achieving superior structural fidelity—setting a new standard in clinical uLDCT denoising. Both the dataset and source code are publicly released.

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Recent publications

Latest Papers

IPv2: An Improved Image Purification Strategy for Real-World Ultra-Low-Dose Lung CT Denoising

Feb 22, 2026

This work addresses the limitations of existing ultra-low-dose lung CT denoising methods, which struggle to effectively suppress noise in both background regions and pulmonary parenchyma and lack a principled strategy for constructing evaluation labels. To overcome these challenges, the authors propose a novel image purification framework employing a three-stage strategy—background removal, controllable noise injection, and denoising—that enhances the model’s joint denoising capability for both regions during training and enables more realistic label construction during testing. This approach represents the first systematic refinement of the image purification pipeline, is compatible with various mainstream denoising architectures, and demonstrates significant improvements in background suppression and lung structure recovery on real patient CT scans acquired at only 2% of standard radiation dose.

0 citationsRead paper

A Denoising Framework for Real-World Ultra-Low Dose Lung CT Images Based on an Image Purification Strategy

Oct 08, 2025

Ultra-low-dose CT (uLDCT) reduces radiation exposure but introduces severe noise, artifacts, and structural misalignment with normal-dose CT (NDCT), degrading the performance of existing denoising methods. To address this, we propose an image purification strategy that, for the first time, generates structurally aligned uLDCT–NDCT paired samples from real clinical data. Building upon this, we design a Frequency-domain Flow Matching (FFM) model that explicitly models the noise distribution in the frequency domain while enforcing anatomical structure consistency via frequency-aware constraints. The resulting dataset and FFM framework significantly improve the denoising performance of multiple state-of-the-art models on real-world uLDCT scans, achieving superior structural fidelity—setting a new standard in clinical uLDCT denoising. Both the dataset and source code are publicly released.

0 citationsRead paper