Ensemble of Radiomics and Convnext for Breast Cancer Diagnosis
This study proposes an integrated approach combining radiomics and the ConvNeXt deep learning model to improve the accuracy of early breast cancer diagnosis from mammographic images. The method uniquely integrates radiomic features with the ConvNeXtV1-small architecture and incorporates a prediction calibration strategy, achieving robust cross-dataset performance on two independent cohorts—RSNA and TecSalud. Experimental results demonstrate that the ensemble model attains an AUC of 0.87 on testing data, significantly outperforming standalone ConvNeXt (AUC: 0.83) and radiomics-based models (AUC: 0.80). These findings underscore the efficacy and generalizability of multimodal fusion in enhancing breast cancer screening.